Improving pregnancy outcomes in humans through studies in sheep
JL Morrison, MJ Berry, KJ Botting… - American Journal …, 2018 - journals.physiology.org
Experimental studies that are relevant to human pregnancy rely on the selection of
appropriate animal models as an important element in experimental design. Consideration …
appropriate animal models as an important element in experimental design. Consideration …
Antenatal corticosteroids: a reappraisal of the drug formulation and dose
We review the history of antenatal corticosteroid therapy (ACS) and present recent
experimental data to demonstrate that this, one of the pillars of perinatal care, has been …
experimental data to demonstrate that this, one of the pillars of perinatal care, has been …
Antenatal corticosteroids: an assessment of anticipated benefits and potential risks
AH Jobe, RL Goldenberg - American journal of obstetrics and gynecology, 2018 - Elsevier
Antenatal corticosteroids are standard of care for pregnancies at risk of preterm delivery
between 24-34 weeks' gestational age. Recent trials demonstrate modest benefits from …
between 24-34 weeks' gestational age. Recent trials demonstrate modest benefits from …
No. 364-Antenatal corticosteroid therapy for improving neonatal outcomes.
No. 364-Antenatal Corticosteroid Therapy for Improving Neonatal Outcomes. - Abstract -
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[HTML][HTML] Low-dose betamethasone-acetate for fetal lung maturation in preterm sheep
AF Schmidt, MW Kemp, J Rittenschober-Böhm… - American journal of …, 2018 - Elsevier
Background Antenatal steroids are standard of care for women who are at risk of preterm
delivery; however, antenatal steroid dosing and formulation have not been evaluated …
delivery; however, antenatal steroid dosing and formulation have not been evaluated …
Antenatal steroids elicited neurodegenerative-associated transcriptional changes in the hippocampus of preterm fetal sheep independent of lung maturation
Background Antenatal steroid therapy for fetal lung maturation is routinely administered to
women at risk of preterm delivery. There is strong evidence to demonstrate benefit from …
women at risk of preterm delivery. There is strong evidence to demonstrate benefit from …
Optimizing antenatal corticosteroid therapy
MW Kemp, AF Schmidt, AH Jobe - Seminars in Fetal and Neonatal …, 2019 - Elsevier
Abstract Treatment with antenatal corticosteroids (ACS) is standard of care for women at risk
of preterm birth between 24 and 34 weeks' gestation. ACS are increasingly used for other …
of preterm birth between 24 and 34 weeks' gestation. ACS are increasingly used for other …
The efficacy of antenatal steroid therapy is dependent on the duration of low-concentration fetal exposure: evidence from a sheep model of pregnancy
Background Antenatal corticosteroids are among the most important and widely used
interventions to improve outcomes for preterm infants. Antenatal corticosteroid dosing …
interventions to improve outcomes for preterm infants. Antenatal corticosteroid dosing …
Betamethasone phosphate reduces the efficacy of antenatal steroid therapy and is associated with lower birthweights when administered to pregnant sheep in …
T Takahashi, EL Fee, Y Takahashi, M Saito… - American journal of …, 2022 - Elsevier
Background Antenatal corticosteroid therapy is a standard of care for women at imminent
risk of preterm labor. However, the optimal (maximum benefit and minimal risk of side …
risk of preterm labor. However, the optimal (maximum benefit and minimal risk of side …
Evaluation of maternal drug exposure following the administration of antenatal corticosteroids during late pregnancy using physiologically‐based pharmacokinetic …
AB Ke, MA Milad - Clinical Pharmacology & Therapeutics, 2019 - Wiley Online Library
Betamethasone and dexamethasone are the most widely studied antenatal corticosteroids
(ACS) administered to pregnant women, just prior to the birth of a preterm neonate, to …
(ACS) administered to pregnant women, just prior to the birth of a preterm neonate, to …