Process analytical technology tools for monitoring pharmaceutical unit operations: a control strategy for continuous process verification
Various frameworks and methods, such as quality by design (QbD), real time release test
(RTRT), and continuous process verification (CPV), have been introduced to improve drug …
(RTRT), and continuous process verification (CPV), have been introduced to improve drug …
Continuous manufacturing in pharmaceutical process development and manufacturing
CL Burcham, AJ Florence… - Annual review of …, 2018 - annualreviews.org
The pharmaceutical industry has found new applications for the use of continuous
processing for the manufacture of new therapies currently in development. The …
processing for the manufacture of new therapies currently in development. The …
Recent progress in continuous manufacturing of oral solid dosage forms
V Vanhoorne, C Vervaet - International Journal of Pharmaceutics, 2020 - Elsevier
Continuous drug product manufacturing is slowly being implemented in the pharmaceutical
industry. Although the benefits related to the quality and cost of continuous manufacturing …
industry. Although the benefits related to the quality and cost of continuous manufacturing …
Twin screw granulation—A literature review
TC Seem, NA Rowson, A Ingram, Z Huang, S Yu… - Powder Technology, 2015 - Elsevier
This review article addresses the currently available literature on twin screw granulation
(TSG). TSG is an emerging technology rapidly gaining interest in the pharmaceutical …
(TSG). TSG is an emerging technology rapidly gaining interest in the pharmaceutical …
A comprehensive review on process and engineering aspects of pharmaceutical wet granulation
P Suresh, I Sreedhar, R Vaidhiswaran… - Chemical Engineering …, 2017 - Elsevier
Wet granulation is a very important unit operation that finds applications in many industries
mainly pharmaceutical and chemical industries. Various granulation technologies in batch …
mainly pharmaceutical and chemical industries. Various granulation technologies in batch …
[HTML][HTML] Effect of particle size distribution on flowability of granulated lactose
Y Kudo, M Yasuda, S Matsusaka - Advanced Powder Technology, 2020 - Elsevier
The flowability of powders used in tableting significantly affects tablet weight and content
uniformity of active pharmaceutical ingredients. Use of granulated materials instead of …
uniformity of active pharmaceutical ingredients. Use of granulated materials instead of …
[图书][B] Continuous manufacturing of pharmaceuticals
P Kleinebudde, J Khinast, J Rantanen - 2017 - books.google.com
A comprehensive look at existing technologies and processes for continuous manufacturing
of pharmaceuticals As rising costs outpace new drug development, the pharmaceutical …
of pharmaceuticals As rising costs outpace new drug development, the pharmaceutical …
Recent trends and future perspective of pharmaceutical wet granulation for better process understanding and product development
P Thapa, J Tripathi, SH Jeong - Powder Technology, 2019 - Elsevier
Current trends in pharmaceutical wet granulation have been shifted from traditional
approach to systematic and modern approaches, enabling the production of highly …
approach to systematic and modern approaches, enabling the production of highly …
Model-based analysis of high shear wet granulation from batch to continuous processes in pharmaceutical production–a critical review
The manufacturing of pharmaceutical dosage forms, which has traditionally been a batch-
wise process, is now also transformed into a series of continuous operations. Some …
wise process, is now also transformed into a series of continuous operations. Some …
Impact of screw configuration on the particle size distribution of granules produced by twin screw granulation
J Vercruysse, A Burggraeve, M Fonteyne… - International journal of …, 2015 - Elsevier
Twin screw granulation (TSG) has been reported by different research groups as an
attractive technology for continuous wet granulation. However, in contrast to fluidized bed …
attractive technology for continuous wet granulation. However, in contrast to fluidized bed …