The HOXA9 transcription factor serves as a molecular orchestrator in cancer stemness,
epithelial-mesenchymal transition (EMT), metastasis, and generation of the tumor …

HOX genes are commonly known for their role in embryonic development, defining the
positional identity of most structures along the anterior–posterior axis. In postembryonic life …

Homeobox (HOX) genes encode highly conserved homeotic transcription factors that play a
crucial role in organogenesis and tissue homeostasis. Their deregulation impacts the …

Our study sought to clarify the effects of microRNA‐139‐5p (miR‐139‐5p) in the
tumorigenesis and progression of oral squamous cell carcinoma (OSCC) by regulating …

Head and neck squamous cell carcinoma (HNSCC) is the sixth most frequently diagnosed
cancer worldwide. However, the clinical outcomes remain unsatisfactory. The aim of this …

Homeobox (HOX) genes are conserved transcription factors which determine the anterior-
posterior body axis patterning. HOXD8 is a member of HOX genes deregulated in several …

MEIS proteins are historically associated with tumorigenesis, metastasis, and invasion in
cancer. MEIS and associated PBXHOX proteins may act as tumor suppressors or …

Background Most cases of lung cancer are diagnosed at advanced stage. Detection of
genetic and epigenetic markers in cell-free DNA (cfDNA) is a promising tool for the …

Keloids are fibroproliferative lesions resulting from an abnormal wound healing process due
to pathological mechanisms that remain incompletely understood. Keloids tend to occur …

Background The expression of CD73 in tumor cells plays a significant role in the production
of adenosine (Ado) that suppresses antitumor effector cells. Methods In this study we …