This review comprehensively summarizes the application of machine learning in solid oral
dosage form development over the past three decades. In both academia and industry …

As is the case with batch-based tableting processes, continuous tablet manufacturing can be
conducted by direct compression or with a granulation step such as dry or wet granulation …

Roller compaction is one stage in a dry granulation process to produce free flowing
granules. Its proper understanding is essential in optimising manufacturing efficiency and …

The development of commercial pharmaceutical formulations can involve extensive
experimentation that generates a large amount of data. Understanding such data and …

We derive a dynamic model for roller compaction process based on Johanson's rolling
theory, which is used to predict the stress and density profiles during the compaction and the …

One of primary goals of the Quality by Design initiative in the pharmaceutical industry is to
reduce variation in the product quality through increased understanding and control of the …

A multi layered, feed forward Artificial Neural Network (ANN) was used to study the effect of
feed mean size, collector dosage and impeller speed on flotation recovery and grade. The …

Roller compaction is a continuous dry granulation process for producing free flowing
granules in order to increase the bulk density and uniformity of pharmaceutical formulations …

The thin layer model is based on the assumption that the deformation of powder during
tableting can be transferred to the roller compaction process, provided that it was …

Dapivirine mucoadhesive gels and freeze-dried tablets were prepared using a 3× 3× 2
factorial design. An artificial neural network (ANN) with multi-layer perception was used to …