Celecoxib for mood disorders: a systematic review and meta-analysis of randomized controlled trials
A Gędek, Z Szular, AZ Antosik, P Mierzejewski… - Journal of Clinical …, 2023 - mdpi.com
The effects of celecoxib on a broad spectrum of mood disorders and on inflammatory
parameters have not yet been comprehensively evaluated. The aim of this study was to …
parameters have not yet been comprehensively evaluated. The aim of this study was to …
Antidepressant effects of NSAIDs in rodent models of depression—A systematic review
C Bay-Richter, G Wegener - Frontiers in Pharmacology, 2022 - frontiersin.org
In recent years much focus has been on neuroimmune mechanisms of depression. As a
consequence, many preclinical and clinical trials have been performed examining potential …
consequence, many preclinical and clinical trials have been performed examining potential …
Increased oxidative stress in the prefrontal cortex as a shared feature of depressive-and PTSD-like syndromes: Effects of a standardized herbal antioxidant
Major depression (MD) and posttraumatic stress disorder (PTSD) share common brain
mechanisms and treatment strategies. Nowadays, the dramatically developing COVID-19 …
mechanisms and treatment strategies. Nowadays, the dramatically developing COVID-19 …
Immunomodulatory effects of new phytotherapy on human macrophages and TLR4-and TLR7/8-mediated viral-like inflammation in mice
O Schapovalova, A Gorlova, J de Munter… - Frontiers in …, 2022 - frontiersin.org
Background While all efforts have been undertaken to propagate the vaccination and
develop remedies against SARS-CoV-2, no satisfactory management of this infection is …
develop remedies against SARS-CoV-2, no satisfactory management of this infection is …
[HTML][HTML] In FUS [1− 359]‐tg mice O, S-dibenzoyl thiamine reduces muscle atrophy, decreases glycogen synthase kinase 3 beta, and normalizes the metabolome
Mutations in the gene encoding the RNA/DNA-binding protein Fused in Sarcoma (FUS)
have been detected in familial amyotrophic lateral sclerosis (ALS) patients. FUS has been …
have been detected in familial amyotrophic lateral sclerosis (ALS) patients. FUS has been …
Resilience and Vulnerability to Stress-Induced Anhedonia: Unveiling Brain Gene Expression and Mitochondrial Dynamics in a Mouse Chronic Stress Depression …
The role of altered brain mitochondrial regulation in psychiatric pathologies, including Major
Depressive Disorder (MDD), has attracted increasing attention. Aberrant mitochondrial …
Depressive Disorder (MDD), has attracted increasing attention. Aberrant mitochondrial …
Disruption of orbitofrontal-hypothalamic projections in a murine ALS model and in human patients
D Bayer, S Antonucci, HP Müller, R Saad… - Translational …, 2021 - Springer
Background Increased catabolism has recently been recognized as a clinical manifestation
of amyotrophic lateral sclerosis (ALS). The hypothalamic systems have been shown to be …
of amyotrophic lateral sclerosis (ALS). The hypothalamic systems have been shown to be …
[HTML][HTML] Lipopolysaccharide triggers exacerbated microglial activation, excessive cytokine release and behavioural disturbances in mice with truncated Fused-in …
CNS inflammation, including microglial activation, in response to peripheral infections are
known to contribute to the pathology of both familial and sporadic neurodegenerative …
known to contribute to the pathology of both familial and sporadic neurodegenerative …
A bioisostere of Dimebon/Latrepirdine delays the onset and slows the progression of pathology in FUS transgenic mice
Aims To assess effects of DF402, a bioisostere of Dimebon/Latrepirdine, on the disease
progression in the transgenic model of amyotrophic lateral sclerosis (ALS) caused by …
progression in the transgenic model of amyotrophic lateral sclerosis (ALS) caused by …
Влияние исследователя на оценку мышечной силы у животных в эксперименте: сравнение автоматизированного теста «перевернутая сетка» и его …
ПР Лебедев, ЕВ Кузубова… - Фармация и …, 2024 - pharmpharm.ru
Investigator’s influence on the muscle strength assessment in animals in experiment:
Comparison of automated “inverted gri Page 1 63 ОРИГИНАЛЬНАЯ СТАТЬЯ Том 12 …
Comparison of automated “inverted gri Page 1 63 ОРИГИНАЛЬНАЯ СТАТЬЯ Том 12 …