Restorative proctocolectomy with ileal pouch–anal anastomosis is an option for most
patients with ulcerative colitis or familial adenomatous polyposis who require colectomy …

Inflammatory bowel disease (IBD) is a chronic and life-long disease characterized by
gastrointestinal tract inflammation. It is caused by the interplay of the host's genetic …

Pouchitis, Crohn's disease of the pouch, cuffitis, polyps, and extraintestinal manifestations of
inflammatory bowel disease are common inflammatory disorders of the ileal pouch. Acute …

Background There is no head‐to‐head trial comparing ustekinumab and vedolizumab in
patients with Crohn's disease (CD) refractory to anti‐tumour necrosis factor (anti‐TNF). Aim …

The American Society of Colon and Rectal Surgeons (ASCRS) is dedicated to ensuring high-
quality patient care by advancing the science, prevention, and management of disorders …

Inflammatory bowel disease (IBD) is a chronic, relapsing disease that severely affects
patients' quality of life. The exact cause of IBD is uncertain, but current studies suggest that …

Although the number of available therapies for the treatment of ulcerative colitis and Crohn's
disease (CD) continues to expand, a significant portion of patients with inflammatory bowel …

Abstract Interleukin-15 (IL-15) is a member of the IL-2 family of cytokines, which use receptor
complexes containing the common gamma (γ c) chain for signaling. IL-15 plays important …

Background & Aims Pouchitis is the most common complication after restorative
proctocolectomy with ileal pouch–anal anastomosis for ulcerative colitis. This American …

Background A subset of patients who undergo total proctocolectomy with ileal pouch–anal
anastomosis (IPAA) creation for ulcerative colitis (UC) will later develop Crohn's disease …