Every optical imaging technique is limited in its penetration depth by scattering occurring in
biological tissues. Possible solutions to overcome this problem consist of limiting the …

Organism-level systems biology aims to identify, analyze, control and design cellular circuits
in organisms. Many experimental and computational approaches have been developed …

Tissue optical clearing technique provides a prospective solution for the application of
advanced optical methods in life sciences. This paper gives a review of recent …

In this review, the authors discuss the underlying principles of SHG and specific factors that
affect the generation properties and describe the essential components of a SHG instrument …

In this article, we discuss the optical immersion method based on refractive index matching
of scatterers (eg, collagen, elastin fibers, cells and cell compartments) and the ground …

This paper aims to review recent progress in optical clearing of the skin and over naturally
turbid biological tissues and blood using this technique in vivo and in vitro with multiphoton …

The image quality of a two-photon microscope is often degraded by wavefront aberrations
induced by the specimen. We demonstrate here that resolution and signal size in two …

Second‐harmonic generation (SHG) microscopy is a fantastic tool for imaging collagen and
probing its hierarchical organization from molecular scale up to tissue architectural level. In …

Although noninvasive, continuous monitoring of glucose concentration in blood and tissues
is one of the most challenging areas in medicine, a wide range of optical techniques has …

A review of specific features and methods of optical clearing and related interaction of light
with tissues is presented. Physical and molecular mechanisms of immersion, compression …