Mass spectrometry (MS) has become a central technique in cancer research. The ability to
analyze various types of biomolecules in complex biological matrices makes it well suited for …

The emerging and powerful field of spatial pharmacology can map the spatial distribution of
drugs and their metabolites, as well as their effects on endogenous biomolecules including …

Covering: 2017 to 2022 Mass spectrometry imaging (MSI) has become a mature molecular
imaging technique that is well-matched for natural product (NP) discovery. Here we present …

Herein, we assess the complementarity and complexity of data that can be detected within
mammalian lipidome mass spectrometry imaging (MSI) via matrix-assisted laser desorption …

Gemcitabine (dFdC) is a common treatment for pancreatic cancer; however, it is thought that
treatment may fail because tumor stroma prevents drug distribution to tumor cells …

Metabolomics samples like human urine or serum contain upwards of a few thousand
metabolites, but individual analytical techniques can only characterize a few hundred …

大脑是人体内结构最精细, 功能最复杂的高级器官, 其化学物质种类众多, 功能多样,
作用机制复杂. 研究证明, 脑中枢神经系统疾病的病变脑组织都涉及到一些神经分子的改变 …

Ethnopharmacological relevance P. lobata and P. thomsonii are medicinal plants with
similar pharmacological functions but different therapeutic effects. A novel method is …

Metabolomics is an interdisciplinary field that aims to study all metabolites< 1500 Da that are
ubiquitously found within all organisms. Metabolomics is experiencing exponential growth …

Gangliosides are highly abundant in the human brain where they are involved in major
biological events. In brain cancers, alterations of ganglioside pattern occur, some of which …