Renal Nano-drug delivery for acute kidney Injury: Current status and future perspectives

HN Geo, DD Murugan, Z Chik, A Norazit, YY Foo… - Journal of Controlled …, 2022 - Elsevier
Acute kidney injury (AKI) causes considerable morbidity and mortality, particularly in the
case of post-cardiac infarction or kidney transplantation; however, the site-specific …

Ensuring global access to COVID-19 vaccines

G Yamey, M Schäferhoff, R Hatchett, M Pate, F Zhao… - The Lancet, 2020 - thelancet.com
The current response to the coronavirus disease 2019 (COVID-19) pandemic involves
aggressive implementation of suppression strategies, such as case identification, quarantine …

Sympathetic nerve traffic overactivity in chronic kidney disease: a systematic review and meta-analysis

G Grassi, A Biffi, G Seravalle, S Bertoli… - Journal of …, 2021 - journals.lww.com
Background: Studies based on microneurographic sympathetic nerve activity (MSNA)
recordings have shown that the sympathetic system is overactivated in chronic kidney …

[HTML][HTML] Asprosin in the paraventricular nucleus induces sympathetic activation and pressor responses via cAMP-dependent ROS production

XL Wang, JX Wang, JL Chen, WY Hao, WZ Xu… - International journal of …, 2022 - mdpi.com
Asprosin is a newly discovered adipokine that is involved in regulating metabolism.
Sympathetic overactivity contributes to the pathogenesis of several cardiovascular diseases …

[HTML][HTML] Risk Factors of Chronic Kidney Disease Progression: Between Old and New Concepts

F Mallamaci, G Tripepi - Journal of Clinical Medicine, 2024 - mdpi.com
Chronic kidney disease (CKD) is a condition characterized by the gradual loss of kidney
function over time and it is a worldwide health issue. The estimated frequency of CKD is …

[HTML][HTML] Sympathetic Denervation Ameliorates Renal Fibrosis via Inhibition of Cellular Senescence

Q Li, Y Deng, L Liu, C Zhang, Y Cai, T Zhang… - Frontiers in …, 2022 - frontiersin.org
Objective Continuous overactivation of the renal sympathetic nerve is considered to be an
important cause of renal fibrosis. Accumulated senescent cells in the damaged kidney have …

[HTML][HTML] Role of α-and β-adrenergic signaling in phenotypic targeting: significance in benign and malignant urologic disease

M Archer, N Dogra, Z Dovey, T Ganta, HS Jang… - Cell Communication and …, 2021 - Springer
The urinary tract is highly innervated by autonomic nerves which are essential in urinary
tract development, the production of growth factors, and the control of homeostasis. These …

[HTML][HTML] Association of baseline electrocardiographic left ventricular hypertrophy with future renal function decline in the general population

S Ikeda, K Shinohara, K Tagawa, T Tohyama… - Scientific reports, 2024 - nature.com
Electrocardiographic left ventricular hypertrophy (LVH) could predict adverse renal
outcomes in patients with hypertension. This study aimed to investigate the association …

Landscape of GPCR expression along the mouse nephron

BG Poll, L Chen, CL Chou… - American Journal of …, 2021 - journals.physiology.org
Kidney transport and other renal functions are regulated by multiple G protein-coupled
receptors (GPCRs) expressed along the renal tubule. The rapid, recent appearance of …

Efficacy and safety of renal denervation for hypertension in patients with chronic kidney disease: a meta-analysis

M Xia, T Liu, D Chen, Y Huang - International Journal of …, 2021 - Taylor & Francis
Background Renal denervation (RDN) is a new treatment for hypertension in patients with
chronic kidney disease (CKD), but its efficacy is still debated. This meta-analysis aimed to …