Type 2 diabetes mellitus is an inflammatory disease and the mechanisms that underlie this
disease, although still incompletely understood, take place in the adipose tissue of obese …

Evidence obtained over the past two decades shows that reactive oxygen species (ROS) are
involved in brain lesions, including those due to cerebral ischemia-reperfusion. The …

Neuropathological evidence indicates that dopaminergic cell death in Parkinson׳ s disease
(PD) involves impairment of mitochondrial complex I, oxidative stress, microglial activation …

Free radicals are known to cause secondary neuronal damage in cerebral
ischemia/reperfusion (I/R). We investigated here the neuroprotective effect of resveratrol, a …

Cancers are the largest cause of mortality and morbidity in industrialized countries. In the
field of the medicinal chemistry of natural products, numerous studies have reported …

Hypoxic–ischemic brain damage is an alarming health and economic problem in spite of the
advances in neonatal care. It can cause mortality or detrimental neurological disorders such …

The mitochondrion is a vital component in cellular energy metabolism and intracellular
signaling processes. Mitochondria are involved in a myriad of complex signaling cascades …

Despite advances in neonatal care, hypoxic-ischemic brain injury is still a serious clinical
problem, which is responsible for many cases of perinatal mortality, cerebral palsy, motor …

Cerebralvascular diseases are the most common high-mortality diseases worldwide.
Despite its global prevalence, effective treatments and therapies need to be explored. Given …

Resveratrol, a natural phenolic compound, has been shown to prevent cardiovascular
diseases and cancer and exhibit neuroprotective effects. In this study, we examined the …