The sequencing of chromosome 21 and the use of models of Down's syndrome in mice have
allowed us to relate genes and sets of genes to the neuropathogenesis of this syndrome …

Approximately 4.5 million Americans have an intellectual or developmental disability.
Concern is increasing about these individuals' nutrition-related behavior and its implications …

The purpose of this study was to evaluate the effect of training on the muscle strength and
dynamic balance ability of adults with Down syndrome (DS). Twenty-five adults with DS …

The life expectancy of adults with Down syndrome has increased dramatically over the last
30 years, leading to increasing numbers of adults with Down syndrome now living into …

The objective of this study was to compare the bone mineral density (BMD) of men with
Down syndrome (DS) to otherwise mentally retarded (MR) men and to investigate whether …

Down syndrome has a prevalence of one in 500 to one in 1,000 live births and is the most
common cause of mental retardation. Most patients are treated in childhood and …

Previous bone comparison studies between subjects with and without Down syndrome (DS)
were performed using bone mineral density (BMD) as the dependent variable, and mainly …

Together, osteoporosis and osteopetrosis comprise a substantial proportion of the bone
diseases that severely affect humans. In order to understand and effectively treat these …

Introduction: In the last decades, life expectancy of persons with Down syndrome (DS) has
dramatically increased and it is estimated that they will be living as long as the general …

Increased incidence of osteoporosis in Down syndrome has been reported, but etiology is
not established. We report low bone turnover markers and bone mineral density (BMD) in a …