Type 2 diabetes mellitus and Alzheimer's disease are both associated with increasing age,
and each increases the risk of development of the other. Epidemiological, clinical …

The prevalence of both Alzheimer's disease (AD) and vascular dementia (VaD) is increasing
with the aging of the population. Studies from the last several years have shown that people …

Background. Pro-inflammatory cytokine production is directly inhibited by acetylcholine
(ACh), and a relationship between total circulating ACh hydrolytic capacity and inflammatory …

Butyrylcholinesterase (BChE), one of the critical human cholinesterases, plays crucial roles
in numerous physiological and pathological processes. Accordingly, it is a striking and at the …

Butyrylcholinesterase (BChE) is an enzyme expressed in multiple organs and abundant in
plasma. BChE can fluctuate in course of several reasons while both hypercholiensterasemia …

Metformin has been used for ages to treat diabetes mellitus due to its safety profile and low
cost. However, metformin has variable pharmacokinetics in patients, and due to its poor oral …

Molecular docking is the major computational technique employed in the early stages of
computer-aided drug discovery. The availability of free software to carry out docking …

Background: Ghrelin is the only orexigenic hormone known to stimulate food intake and
promote obesity and insulin resistance. We recently showed that plasma ghrelin is …

The results of epidemiological and pathophysiological studies suggest that type 2 diabetes
mellitus (T2DM) may predispose to Alzheimer's disease (AD). The two conditions present …

Objective We investigated the relationship between butyrylcholinesterase (BuChE) and
cardiovascular risk factors in young male and female. Design and methods The study …