Tumor-associated macrophages in cancer: recent advancements in cancer nanoimmunotherapies

N Kumari, SH Choi - Journal of Experimental & Clinical Cancer Research, 2022 - Springer
Cancer immunotherapy has emerged as a novel cancer treatment, although recent
immunotherapy trials have produced suboptimal outcomes, with durable responses seen …

Nanotechnology for boosting cancer immunotherapy and remodeling tumor microenvironment: the horizons in cancer treatment

S Gao, X Yang, J Xu, N Qiu, G Zhai - ACS nano, 2021 - ACS Publications
Immunotherapy that harnesses the human immune system to fight cancer has received
widespread attention and become a mainstream strategy for cancer treatment. Cancer …

Metal-polyDNA nanoparticles reconstruct osteoporotic microenvironment for enhanced osteoporosis treatment

X Liu, F Li, Z Dong, C Gu, D Mao, J Chen, L Luo… - Science …, 2023 - science.org
Current clinical approaches to osteoporosis primarily target osteoclast biology, overlooking
the synergistic role of bone cells, immune cells, cytokines, and inorganic components in …

Development of nanotechnology-mediated precision radiotherapy for anti-metastasis and radioprotection

Y Pan, W Tang, W Fan, J Zhang, X Chen - Chemical Society Reviews, 2022 - pubs.rsc.org
Radiotherapy (RT), including external beam RT and internal radiation therapy, uses high-
energy ionizing radiation to kill tumor cells. However, ionizing radiation inevitably damages …

Nanomedicine embraces cancer radio-immunotherapy: mechanism, design, recent advances, and clinical translation

H Li, Q Luo, H Zhang, X Ma, Z Gu, Q Gong… - Chemical Society …, 2023 - pubs.rsc.org
Cancer radio-immunotherapy, integrating external/internal radiation therapy with immuno-
oncology treatments, emerges in the current management of cancer. A growing number of …

Tailoring nanomaterials for targeting tumor‐associated macrophages

M Ovais, M Guo, C Chen - Advanced materials, 2019 - Wiley Online Library
Advances in the field of nanotechnology together with an increase understanding of tumor
immunology have paved the way for the development of more personalized cancer immuno …

Immunostimulant hydrogel-guided tumor microenvironment reprogramming to efficiently potentiate macrophage-mediated cellular phagocytosis for systemic cancer …

JL Liang, XK Jin, GF Luo, SM Zhang, QX Huang… - ACS …, 2023 - ACS Publications
Macrophage-mediated cellular phagocytosis (MMCP) plays a critical role in conducting
antitumor immunotherapy but is usually impaired by the intrinsic phagocytosis evading …

Cancer cell membrane-coated nanoparticles for bimodal imaging-guided photothermal therapy and docetaxel-enhanced immunotherapy against cancer

Q Chen, L Zhang, L Li, M Tan, W Liu, S Liu… - Journal of …, 2021 - Springer
Background Mono-therapeutic modality has limitations in combating metastatic lesions with
complications. Although emerging immunotherapy exhibits preliminary success, solid …

Radiolabeling nanomaterials for multimodality imaging: New insights into nuclear medicine and cancer diagnosis

J Ge, Q Zhang, J Zeng, Z Gu, M Gao - Biomaterials, 2020 - Elsevier
Nuclear medicine imaging has been developed as a powerful diagnostic approach for
cancers by detecting gamma rays directly or indirectly from radionuclides to construct …

Immunosuppressive cells in cancer: mechanisms and potential therapeutic targets

Y Tie, F Tang, Y Wei, X Wei - Journal of hematology & oncology, 2022 - Springer
Immunotherapies like the adoptive transfer of gene-engineered T cells and immune
checkpoint inhibitors are novel therapeutic modalities for advanced cancers. However, some …