Multi‐perspectives and challenges in identifying B‐cell epitopes

N Kumar, N Bajiya, S Patiyal, GPS Raghava - Protein Science, 2023 - Wiley Online Library
The identification of B‐cell epitopes (BCEs) in antigens is a crucial step in developing
recombinant vaccines or immunotherapies for various diseases. Over the past four decades …

In silico design of a polypeptide as a vaccine candidate against ascariasis

FMD Evangelista, AHM van Vliet, SP Lawton… - Scientific reports, 2023 - nature.com
Ascariasis is the most prevalent zoonotic helminthic disease worldwide, and is responsible
for nutritional deficiencies, particularly hindering the physical and neurological development …

AbAgIntPre: A deep learning method for predicting antibody-antigen interactions based on sequence information

Y Huang, Z Zhang, Y Zhou - Frontiers in Immunology, 2022 - frontiersin.org
Introduction Antibody-mediated immunity is an essential part of the immune system in
vertebrates. The ability to specifically bind to antigens allows antibodies to be widely used in …

Women in the european virus bioinformatics center

F Hufsky, A Abecasis, P Agudelo-Romero, M Bletsa… - Viruses, 2022 - mdpi.com
Viruses are the cause of a considerable burden to human, animal and plant health, while on
the other hand playing an important role in regulating entire ecosystems. The power of new …

Rational design of a novel multi-epitope peptide-based vaccine against Onchocerca volvulus using transmembrane proteins

RA Shey, SM Ghogomu, DN Nebangwa… - Frontiers in Tropical …, 2022 - frontiersin.org
Almost a decade ago, it was recognized that the global elimination of onchocerciasis by
2030 will not be feasible without, at least, an effective prophylactic and/or therapeutic …

BeeTLe: A Framework for Linear B-Cell Epitope Prediction and Classification

X Yuan - Joint European Conference on Machine Learning and …, 2023 - Springer
The process of identifying and characterizing B-cell epitopes, which are the portions of
antigens recognized by antibodies, is important for our understanding of the immune system …

[PDF][PDF] One-Health Approach to the Computational Design of a Lipoprotein-Based Multi-Epitope Vaccine Against Human and Livestock Tuberculosis

RA Shey, GT Nchanji, TYA Tangan, NE Yaah… - 2025 - preprints.org
Tuberculosis (TB) remains a major cause of ill health and one of the leading causes of death
worldwide, with about 1.25 million deaths estimated in 2023. Control measures have …

Feature Selection Using Hybrid Black Hole Genetic Algorithm in Multi-label Datasets

H Khandelwal, J Valadi - … Computing for Problem Solving: Proceedings of …, 2023 - Springer
In multi-label classification, each instance is assigned to a group of labels. Due to its
expanding use in applications across domains, multi-label classification has gained …