[HTML][HTML] IMI—the dynamic choroid: new insights, challenges, and potential significance for human myopia

LA Ostrin, E Harb, DL Nickla, SA Read… - … & visual science, 2023 - jov.arvojournals.org
The choroid is the richly vascular layer of the eye located between the sclera and Bruch's
membrane. Early studies in animals, as well as more recent studies in humans, have …

[HTML][HTML] Longitudinal changes and predictive value of choroidal thickness for myopia control after repeated low-level red-light therapy

R Xiong, Z Zhu, Y Jiang, W Wang, J Zhang, Y Chen… - Ophthalmology, 2023 - Elsevier
Purpose To evaluate longitudinal changes in macular choroidal thickness (mCT) in myopic
children treated for 1 year with repeated low-level red-light (RLRL) therapy and their …

Repeated Low-level Red-light Therapy: The Next Wave in Myopia Management?

AD Salzano, S Khanal, NL Cheung… - Optometry and Vision …, 2022 - journals.lww.com
Significance: Exposure to long-wavelength light has been proposed as a potential
intervention to slow myopia progression in children. This article provides an evidence-based …

[HTML][HTML] Lowering intraocular pressure: a potential approach for controlling high myopia progression

P Wang, S Chen, Y Liu, F Lin, Y Song… - … & Visual Science, 2021 - tvst.arvojournals.org
High myopia is among the most common causes of vision impairment, and it is mainly
characterized by abnormal elongation of the axial length, leading to pathologic changes in …

Establishment of an in vitro choroid complex system for vascular response screening

H Jeong, D Lee, K Negishi, K Tsubota, T Kurihara - Scientific reports, 2024 - nature.com
The choroid, a vascularized tissue situated between the retina and the sclera, plays a crucial
role in maintaining ocular homeostasis. Despite its significance, research on choroidal …

Changes in the choroidal thickness of children wearing MiSight to control myopia

FL Prieto-Garrido, C Villa-Collar… - Journal of Clinical …, 2022 - mdpi.com
Background: Due to the importance of choroidal thickness in the development of myopia,
this study examined the effect of MiSight contact lenses (CLs) on the choroidal thickness of …

Assessment of macular choroidal and retinal thickness: a cohort study in Tibetan healthy children

Y Yao, J Fu, J Liu, L Li, W Chen, Z Meng - Scientific Reports, 2024 - nature.com
This research investigates the distribution, progressive changes, and contributing factors of
macular choroidal and retinal thickness in Tibetan children utilizing swept-source optical …

Vascular endothelial growth factor from retinal pigment epithelium is essential in choriocapillaris and axial length maintenance

Y Zhang, H Jeong, K Mori, SI Ikeda, C Shoda… - PNAS …, 2022 - academic.oup.com
Myopia, which prevalence is rapidly increasing, causes visual impairment; however, the
onset mechanism of pathological axial length (AL) elongation remains unclear. A highly …

Lrpap1 deficiency leads to myopia through TGF-β-induced apoptosis in zebrafish

S Liu, T Chen, B Chen, Y Liu, X Lu, J Li - Cell Communication and …, 2022 - Springer
Background Frameshift mutations in LRPAP1 are responsible for autosomal recessive high
myopia in human beings but its underlying mechanism remains elusive. This study aims to …

Association between choriocapillaris perfusion and axial elongation in children using defocus incorporated multiple segments (DIMS) spectacle lenses

X Li, J Hu, Z Peng, S Chen, L Sun, K Wang, Y Li… - Eye, 2023 - nature.com
Purpose To investigate choroidal and ocular biological variables that influence axial length
(AL) elongation in children wearing defocused incorporated multiple segments (DIMS) …