Managing efficacy and toxicity of drugs: Targeted delivery and excretion
Medicine is a natural companion of mankind in the present era for mere survival from the
deadly diseases in ever-increasing polluted environments. Hence, in recent years, major …
deadly diseases in ever-increasing polluted environments. Hence, in recent years, major …
Evidence for dual site binding of nile blue a toward DNA: Spectroscopic, thermodynamic, and molecular modeling studies
Binding of Nile Blue (NB) with calf thymus DNA has been studied using molecular modeling,
spectroscopic, and thermodynamic techniques. Our study revealed that NB binds to the DNA …
spectroscopic, and thermodynamic techniques. Our study revealed that NB binds to the DNA …
Probing the intercalation of noscapine from sodium dodecyl sulfate micelles to calf thymus deoxyribose nucleic acid: a mechanistic approach
N Maurya, KA Alzahrani, R Patel - ACS omega, 2019 - ACS Publications
Noscapine (NOS) is efficient in inhibiting cellular proliferation and induces apoptosis in
nonsmall cell, lung, breast, lymphatic, and prostate cancers. The micelle-assisted drug …
nonsmall cell, lung, breast, lymphatic, and prostate cancers. The micelle-assisted drug …
Exploring the Nucleobase-Specific Hydrophobic Interaction of Cryptolepine Hydrate with RNA and Its Subsequent Sequestration
The study of the interactions of drug molecules with genetic materials plays a key role
underlying the development of new drugs for many life-threatening diseases in …
underlying the development of new drugs for many life-threatening diseases in …
A comparison on the biochemical activities of Fluorescein disodium, Rose Bengal and Rhodamine 101 in the light of DNA binding, antimicrobial and cytotoxic study
Abstract Biochemical activities of Fluorescein, Rose Bengal and Rhodamine 101 were
studied by DNA binding, antibacterial and cytotoxic studies. DNA binding studies were done …
studied by DNA binding, antibacterial and cytotoxic studies. DNA binding studies were done …
Ionic liquid green assembly-mediated migration of piperine from calf-thymus DNA: a new possibility of the tunable drug delivery system
Biocompatible surface-active ionic liquid (SAIL) was used first to study the deintercalation
process of a well-known natural compound piperine (PIP) as an anticancer drug, obtained …
process of a well-known natural compound piperine (PIP) as an anticancer drug, obtained …
Origin of unusually high fluorescence anisotropy of 3-hydroxyflavone in water: Formation of probe–solvent cage-like cluster
S Das, S Chakrabarty… - The Journal of Physical …, 2019 - ACS Publications
Based on the unusually high fluorescence anisotropy (FA) of 3-hydroxyflavone (3HF) in
water medium in contrast to the very low FA of its methoxy counterpart (3MF), our proposition …
water medium in contrast to the very low FA of its methoxy counterpart (3MF), our proposition …
Exploring the binding interaction of Bis-benzimidazoles with BSA and relocation of bound drug from BSA to DNA
P Das, P Mandal, D Shit, S Pramanik - Journal of Molecular Structure, 2024 - Elsevier
In recent years Bis-benzimidazole derivatives have gained much research interest due to
their regulatory role in biological reactions to control diseases. Therefore, probing the …
their regulatory role in biological reactions to control diseases. Therefore, probing the …
Liposome‐Based Delivery of a Bis‐benzimidazole Derivative to Duplex DNA: A Spectroscopic Study
D Shit, P Mandal, P Das, S Pramanik - ChemistrySelect, 2024 - Wiley Online Library
Due to the immense pharmacological significance, the interaction of small molecules with
liposome and the exact knowledge of their binding location and distribution within the lipid …
liposome and the exact knowledge of their binding location and distribution within the lipid …
Unraveling the binding interaction of a bioactive pyrazole-based probe with serum proteins: Relative concentration dependent 1: 1 and 2: 1 probe-protein …
P Kundu, N Chattopadhyay - Biophysical Chemistry, 2018 - Elsevier
Molecular interactions and binding of probes/drugs with biomacromolecular systems are of
fundamental importance in understanding the mechanism of action and hence designing of …
fundamental importance in understanding the mechanism of action and hence designing of …