The potential use of bacteriophages as antibacterial agents against Klebsiella pneumoniae
O Gholizadeh, HEG Ghaleh, M Tat, R Ranjbar… - Virology Journal, 2024 - Springer
One of the most common bacteria that cause nosocomial infections is Klebsiella pneumonia
(K. pneumoniae), especially in patients who are very sick and admitted to the intensive care …
(K. pneumoniae), especially in patients who are very sick and admitted to the intensive care …
Differentiation of hypervirulent and classical Klebsiella pneumoniae with acquired drug resistance
TA Russo, CL Alvarado, CJ Davies, ZJ Drayer… - Mbio, 2024 - Am Soc Microbiol
Distinguishing hypervirulent (hvKp) from classical Klebsiella pneumoniae (cKp) strains is
important for clinical care, surveillance, and research. Some combinations of iucA, iroB, peg …
important for clinical care, surveillance, and research. Some combinations of iucA, iroB, peg …
Animal models of Klebsiella pneumoniae mucosal infections
L Assoni, AJM Couto, B Vieira, B Milani… - Frontiers in …, 2024 - frontiersin.org
Klebsiella pneumoniae is among the most relevant pathogens worldwide, causing high
morbidity and mortality, which is worsened by the increasing rates of antibiotic resistance. It …
morbidity and mortality, which is worsened by the increasing rates of antibiotic resistance. It …
Heptavalent O-Antigen Bioconjugate Vaccine Exhibiting Differential Functional Antibody Responses Against Diverse Klebsiella pneumoniae Isolates
PL Wantuch, CJ Knoot, LS Robinson… - The Journal of …, 2024 - academic.oup.com
Klebsiella pneumoniae is the leading cause of neonatal sepsis and is increasingly difficult to
treat owing to antibiotic resistance. Vaccination represents a tractable approach to combat …
treat owing to antibiotic resistance. Vaccination represents a tractable approach to combat …
A novel antivirulent compound fluorothiazinone inhibits Klebsiella pneumoniae biofilm in vitro and suppresses model pneumonia
SV Tsarenko, NA Zigangirova, AV Soloveva… - The Journal of …, 2023 - nature.com
The problematic treatment of infections caused by multiple-resistant Klebsiella, especially in
ICU, is the leading cause of prolonged hospitalization and high mortality rates. The use of …
ICU, is the leading cause of prolonged hospitalization and high mortality rates. The use of …
Diverse polysaccharide production and biofilm formation abilities of clinical Klebsiella pneumoniae
RL Beckman IV, E Cella, T Azarian… - npj Biofilms and …, 2024 - nature.com
Klebsiella pneumoniae infections have become a growing threat for human health. The lack
of understanding of the relationship between antibiotic resistance, mucoviscosity, and …
of understanding of the relationship between antibiotic resistance, mucoviscosity, and …
Anti-capsule human monoclonal antibodies protect against hypervirulent and pandrug-resistant Klebsiella pneumoniae
E Roscioli, VZ Galli Fonseca, SS Bosch, I Paciello… - bioRxiv, 2024 - biorxiv.org
The silent pandemic caused by antimicrobial resistance (AMR) requires innovative
therapeutic approaches. Human monoclonal antibodies (mAbs), which are among the most …
therapeutic approaches. Human monoclonal antibodies (mAbs), which are among the most …
Polyamine-Mediated Sensitization of Klebsiella pneumoniae to Macrolides through a Dual Mode of Action
JME Adams, PB Moulding… - ACS Infectious …, 2024 - ACS Publications
Chemicals bacteria encounter at the infection site could shape their stress and antibiotic
responses; such effects are typically undetected under standard lab conditions. Polyamines …
responses; such effects are typically undetected under standard lab conditions. Polyamines …
Polyproline peptide targets Klebsiella pneumoniae polysaccharides to collapse biofilms
L De los Santos, RL Beckman, C DeBarro… - Cell Reports Physical …, 2024 - cell.com
Hypervirulent Klebsiella pneumoniae is known for its increased extracellular polysaccharide
production. Biofilm matrices of hypervirulent K. pneumoniae have increased polysaccharide …
production. Biofilm matrices of hypervirulent K. pneumoniae have increased polysaccharide …
Molecular characterization and virulence profile of Klebsiella pneumoniae and Klebsiella oxytoca isolated from ill cats and dogs in Portugal
Klebsiella spp. are important pathogens of humans and companion animals such as cats
and dogs, capable of causing severe life-threatening diseases. The aim of this study was to …
and dogs, capable of causing severe life-threatening diseases. The aim of this study was to …