Mesenchymal stem cell derived-exosomes: a modern approach in translational medicine

S Nikfarjam, J Rezaie, NM Zolbanin, R Jafari - Journal of translational …, 2020 - Springer
Mesenchymal stem cells (MSCs) have captured great attention in regenerative medicine for
over a few decades by virtue of their differentiation capacity, potent immunomodulatory …

Mesenchymal stromal cell secretome: influencing therapeutic potential by cellular pre-conditioning

JR Ferreira, GQ Teixeira, SG Santos… - Frontiers in …, 2018 - frontiersin.org
Mesenchymal stromal cells (MSCs) are self-renewing, culture-expandable adult stem cells
that have been isolated from a variety of tissues, and possess multipotent differentiation …

Mesenchymal stem/stromal cell-based therapy: mechanism, systemic safety and biodistribution for precision clinical applications

WZ Zhuang, YH Lin, LJ Su, MS Wu, HY Jeng… - Journal of biomedical …, 2021 - Springer
Mesenchymal stem/stromal cells (MSCs) are a promising resource for cell-based therapy
because of their high immunomodulation ability, tropism towards inflamed and injured …

Mechanisms of mesenchymal stem/stromal cell function

JL Spees, RH Lee, CA Gregory - Stem cell research & therapy, 2016 - Springer
The past decade has seen an explosion of research directed toward better understanding of
the mechanisms of mesenchymal stem/stromal cell (MSC) function during rescue and repair …

MSC exosome works through a protein-based mechanism of action

WS Toh, RC Lai, B Zhang, SK Lim - Biochemical Society …, 2018 - portlandpress.com
Mesenchymal stem cell (MSC) exosome specifically defines the 50–200 nm vesicles that are
secreted into the extracellular space when multivesicular bodies in the MSC fuse with the …

Applications of mesenchymal stem cells in skin regeneration and rejuvenation

H Jo, S Brito, BM Kwak, S Park, MG Lee… - International journal of …, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) are multipotent stem cells derived from adult stem cells.
Primary MSCs can be obtained from diverse sources, including bone marrow, adipose …

Flexible shape-memory scaffold for minimally invasive delivery of functional tissues

M Montgomery, S Ahadian, L Davenport Huyer… - Nature materials, 2017 - nature.com
Despite great progress in engineering functional tissues for organ repair, including the heart,
an invasive surgical approach is still required for their implantation. Here, we designed an …

Paracrine mechanisms of mesenchymal stem cells in tissue repair

M Gnecchi, P Danieli, G Malpasso… - Mesenchymal Stem Cells …, 2016 - Springer
Tissue regeneration from transplanted mesenchymal stromal cells (MSC) either through
transdifferentiation or cell fusion was originally proposed as the principal mechanism …

Mesenchymal stem cell exosomes

RC Lai, RWY Yeo, SK Lim - Seminars in cell & developmental biology, 2015 - Elsevier
MSCs are an extensively used cell type in clinical trials today. The initial rationale for their
clinical testing was based on their differentiation potential. However, the lack of correlation …

Concise review: mesenchymal stem cell-based drug delivery: the good, the bad, the ugly, and the promise

TEG Krueger, DLJ Thorek… - Stem cells …, 2018 - academic.oup.com
The development of mesenchymal stem cells (MSCs) as cell-based drug delivery vectors for
numerous clinical indications, including cancer, has significant promise. However, a …