Mesenchymal stem cell derived-exosomes: a modern approach in translational medicine
Mesenchymal stem cells (MSCs) have captured great attention in regenerative medicine for
over a few decades by virtue of their differentiation capacity, potent immunomodulatory …
over a few decades by virtue of their differentiation capacity, potent immunomodulatory …
Mesenchymal stromal cell secretome: influencing therapeutic potential by cellular pre-conditioning
JR Ferreira, GQ Teixeira, SG Santos… - Frontiers in …, 2018 - frontiersin.org
Mesenchymal stromal cells (MSCs) are self-renewing, culture-expandable adult stem cells
that have been isolated from a variety of tissues, and possess multipotent differentiation …
that have been isolated from a variety of tissues, and possess multipotent differentiation …
Mesenchymal stem/stromal cell-based therapy: mechanism, systemic safety and biodistribution for precision clinical applications
WZ Zhuang, YH Lin, LJ Su, MS Wu, HY Jeng… - Journal of biomedical …, 2021 - Springer
Mesenchymal stem/stromal cells (MSCs) are a promising resource for cell-based therapy
because of their high immunomodulation ability, tropism towards inflamed and injured …
because of their high immunomodulation ability, tropism towards inflamed and injured …
Mechanisms of mesenchymal stem/stromal cell function
JL Spees, RH Lee, CA Gregory - Stem cell research & therapy, 2016 - Springer
The past decade has seen an explosion of research directed toward better understanding of
the mechanisms of mesenchymal stem/stromal cell (MSC) function during rescue and repair …
the mechanisms of mesenchymal stem/stromal cell (MSC) function during rescue and repair …
MSC exosome works through a protein-based mechanism of action
Mesenchymal stem cell (MSC) exosome specifically defines the 50–200 nm vesicles that are
secreted into the extracellular space when multivesicular bodies in the MSC fuse with the …
secreted into the extracellular space when multivesicular bodies in the MSC fuse with the …
Applications of mesenchymal stem cells in skin regeneration and rejuvenation
Mesenchymal stem cells (MSCs) are multipotent stem cells derived from adult stem cells.
Primary MSCs can be obtained from diverse sources, including bone marrow, adipose …
Primary MSCs can be obtained from diverse sources, including bone marrow, adipose …
Flexible shape-memory scaffold for minimally invasive delivery of functional tissues
M Montgomery, S Ahadian, L Davenport Huyer… - Nature materials, 2017 - nature.com
Despite great progress in engineering functional tissues for organ repair, including the heart,
an invasive surgical approach is still required for their implantation. Here, we designed an …
an invasive surgical approach is still required for their implantation. Here, we designed an …
Paracrine mechanisms of mesenchymal stem cells in tissue repair
M Gnecchi, P Danieli, G Malpasso… - Mesenchymal Stem Cells …, 2016 - Springer
Tissue regeneration from transplanted mesenchymal stromal cells (MSC) either through
transdifferentiation or cell fusion was originally proposed as the principal mechanism …
transdifferentiation or cell fusion was originally proposed as the principal mechanism …
Mesenchymal stem cell exosomes
MSCs are an extensively used cell type in clinical trials today. The initial rationale for their
clinical testing was based on their differentiation potential. However, the lack of correlation …
clinical testing was based on their differentiation potential. However, the lack of correlation …
Concise review: mesenchymal stem cell-based drug delivery: the good, the bad, the ugly, and the promise
TEG Krueger, DLJ Thorek… - Stem cells …, 2018 - academic.oup.com
The development of mesenchymal stem cells (MSCs) as cell-based drug delivery vectors for
numerous clinical indications, including cancer, has significant promise. However, a …
numerous clinical indications, including cancer, has significant promise. However, a …