Mitochondria are the main source of reactive oxygen species (ROS) in cells. Early studies
have shown that mitochondrial reactive oxygen species (mROS) are related to the …

Nitric oxide (NO) is a small free radical with critical signaling roles in physiology and
pathophysiology. The generation of sufficient NO levels to regulate the resistance of the …

The insufficient intracellular H2O2 level in tumor cells is closely associated with the limited
efficacy of chemodynamic therapy (CDT). Despite tremendous efforts, engineering CDT …

Reperfusion injury, the paradoxical tissue response that is manifested by blood flow-
deprived and oxygen-starved organs following the restoration of blood flow and tissue …

Byproducts of normal mitochondrial metabolism and homeostasis include the buildup of
potentially damaging levels of reactive oxygen species (ROS), Ca2+, etc., which must be …

Mitochondria serves a primary role in energy maintenance but also function to govern levels
of mitochondria-derived reactive oxygen species (mROS). ROS have long been established …

ROS (superoxide and oxygen peroxide in this paper) play a dual role as signalling
molecules and strong oxidizing agents leading to oxidative stress. Their production mainly …

Reactive oxygen species (ROS) play an important role in cardiovascular diseases, and one
important source for ROS are mitochondria. Emission of ROS from mitochondria is the net …

Current scientific debates center on the impact of lipids and mitochondrial function on
diverse aspects of human health, nutrition and disease, among them the association of …

Reactive oxygen species (ROS) are recognized both as damaging molecules and
intracellular signaling entities. In addition to its role in ATP generation, the mitochondrial …