Cellular therapies using regulatory T (Treg) cells are currently undergoing clinical trials for
the treatment of autoimmune diseases, transplant rejection and graft-versus-host disease. In …

Natural killer (NK) cells are unique immune effectors able to kill cancer cells by direct
recognition of surface ligands, without prior sensitization. Allogeneic NK transfer is a highly …

Cancer immunotherapy has been firmly established as a new milestone for cancer therapy,
with the development of multiple immune cells as therapeutic tools. Natural killer (NK) cells …

Objective Regulatory T cells (Tregs) prevent autoimmunity and control inflammation.
Consequently, any autoimmune or inflammatory disease reveals a Treg insufficiency. As low …

The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …

Depletion of regulatory T (TReg) cells in otherwise healthy individuals leads to multi-organ
autoimmune disease and inflammation. This indicates that in a normal immune system …

There is burgeoning interest in the ability to detect inflammatory markers in response to
stress within naturally occurring social contexts and/or across multiple time points per day …

Purpose: To evaluate the safety, efficacy, and immunobiological correlates of allogeneic NK-
cell–based therapy in primary chemotherapy-refractory or relapsed high-risk …

Most autoimmune diseases (AID) are linked to an imbalance between autoreactive effector T
cells (Teffs) and regulatory T cells (Tregs). While blocking Teffs with immunosuppression …

Scientific insights into the human immune system have recently led to unprecedented
breakthroughs in immunotherapy. In the twenty-first century, drugs and cell-based therapies …