Vascular mechanisms of testosterone: the non-genomic point of view

M Lorigo, M Mariana, MC Lemos, E Cairrao - The Journal of steroid …, 2020 - Elsevier
Testosterone (T) is the predominant endogenous androgen in the bloodstream. At the
vascular level, T presents genomic and non-genomic effects, and both effects may overlap …

Neurobiology of puberty and its disorders

SF Witchel, TM Plant - Handbook of Clinical Neurology, 2021 - Elsevier
Puberty, which in humans is considered to include both gonadarche and adrenarche, is the
period of becoming capable of reproducing sexually and is recognized by maturation of the …

Simultaneous analysis by LC–MS/MS of 22 ketosteroids with hydroxylamine derivatization and underivatized estradiol from human plasma, serum and prostate tissue

MR Häkkinen, T Murtola, R Voutilainen… - … of pharmaceutical and …, 2019 - Elsevier
This study describes a validated LC–MS/MS method for assaying 23 steroids within a single
run from 150 μl of human plasma, serum or prostatic tissue homogenate. Isotope-labeled …

A quantitative analysis of total and free 11-oxygenated androgens and its application to human serum and plasma specimens using liquid-chromatography tandem …

P Caron, V Turcotte, C Guillemette - Journal of Chromatography A, 2021 - Elsevier
Abstract Bioactive 11-oxygenated C 19 adrenal-derived steroids (11-oxy C 19) are
potentially relevant in diverse endocrine and metabolic contexts. We report the development …

The 11β-hydroxyandrostenedione pathway and C11-oxy C21 backdoor pathway are active in benign prostatic hyperplasia yielding 11keto-testosterone and 11keto …

T Du Toit, AC Swart - The Journal of Steroid Biochemistry and Molecular …, 2020 - Elsevier
In clinical approaches to benign prostatic hyperplasia (BPH) and prostate cancer (PCa),
steroidogenesis or the disruption thereof is the main thrust in treatments restricting active …

[HTML][HTML] Determination of steroid hormones in grey seal (Halichoerus grypus) blood plasma using convergence chromatography tandem mass spectrometry

STL Sait, V Survilienė, M Jüssi, SV Gonzalez… - Talanta, 2023 - Elsevier
A hybrid solid phase extraction (HybridSPE) protocol tailored to ultra-performance
convergence chromatography tandem mass spectrometry (UPC 2-MS/MS) was developed …

What's in a whisker? High-throughput analysis of twenty-eight C19 and C21 steroids in mammalian whiskers by ultra-performance convergence chromatography …

N Lübcker, LM Bloem, T Du Toit, P Swart… - … of Chromatography B, 2020 - Elsevier
Obtaining longitudinal endocrinological data from free-ranging animals remains
challenging. Steroid hormones can be extracted sequentially from non-invasively sampled …

Rapid and efficient chiral method development for lamivudine and tenofovir disoproxil fumarate fixed dose combination using ultra-high performance supercritical fluid …

M Kurmi, K Jayaraman, S Natarajan, GS Kumar… - … of Chromatography A, 2020 - Elsevier
Fixed dose combination (FDC) of tenofovir disoproxil fumarate (TDF) and lamivudine (3TC)
is one of the most preferred FDC for the treatment of acquired immunodeficiency syndrome …

Residue and dietary risk assessment of chiral cyflumetofen in apple

J Guo, M Li, Y Liu, F Wang, Z Kong, Y Sun, J Lu, N Jin… - Molecules, 2018 - mdpi.com
Ultra-performance convergence chromatography is an environmentally-friendly analytical
method that uses dramatically reduced amounts of organic solvents. In addition, a robust …

Steroid hormone analysis of adolescents and young women with polycystic ovarian syndrome and adrenocortical dysfunction using UPC2-MS/MS

AC Swart, T du Toit, E Gourgari, M Kidd, M Keil… - Pediatric …, 2021 - nature.com
BACKGROUND We recently identified 35 women with polycystic ovarian syndrome (PCOS)
who exhibited features of micronodular adrenocortical hyperplasia. Steroid hormone …