Nanocarrier drug delivery systems: characterization, limitations, future perspectives and implementation of artificial intelligence

SZ Alshawwa, AA Kassem, RM Farid, SK Mostafa… - Pharmaceutics, 2022 - mdpi.com
There has been an increasing demand for the development of nanocarriers targeting
multiple diseases with a broad range of properties. Due to their tiny size, giant surface area …

Single-Molecule Spectroscopy and Super-Resolution Mapping of Physicochemical Parameters in Living Cells

MA Steves, C He, K Xu - Annual Review of Physical Chemistry, 2024 - annualreviews.org
By superlocalizing the positions of millions of single molecules over many camera frames, a
class of super-resolution fluorescence microscopy methods known as single-molecule …

Can super-resolution microscopy become a standard characterization technique for materials chemistry?

S Dhiman, T Andrian, BS Gonzalez, MME Tholen… - Chemical …, 2022 - pubs.rsc.org
The characterization of newly synthesized materials is a cornerstone of all chemistry and
nanotechnology laboratories. For this purpose, a wide array of analytical techniques have …

Single particle chemical characterisation of nanoformulations for cargo delivery

C Saunders, CA de Villiers, MM Stevens - The AAPS Journal, 2023 - Springer
Nanoparticles can encapsulate a range of therapeutics, from small molecule drugs to
sensitive biologics, to significantly improve their biodistribution and biostability. Whilst the …

Biomolecule–polymer hybrid compartments: combining the best of both worlds

CE Meyer, SL Abram, I Craciun… - Physical Chemistry …, 2020 - pubs.rsc.org
Compartmentalization is a fundamental principle in biology that is needed for the temporal
and spatial separation of chemically incompatible reactions and biomolecules. Nano-or …

Spectroscopic single-molecule localization microscopy: applications and prospective

B Brenner, C Sun, FM Raymo, HF Zhang - Nano convergence, 2023 - Springer
Single-molecule localization microscopy (SMLM) breaks the optical diffraction limit by
numerically localizing sparse fluorescence emitters to achieve super-resolution imaging …

Super‐resolution fluorescence microscopy‐based single‐molecule spectroscopy

D Jeong, D Kim - Bulletin of the Korean Chemical Society, 2022 - Wiley Online Library
The rise of super‐resolution fluorescence microscopy (SRM) has revolutionized our
understanding of the nanoscale world. SRM has recently been correlated with spectroscopy …

Monolithic dual-wedge prism-based spectroscopic single-molecule localization microscopy

KH Song, B Brenner, WH Yeo, J Kweon, Z Cai… - …, 2022 - degruyter.com
By manipulating the spectral dispersion of detected photons, spectroscopic single-molecule
localization microscopy (sSMLM) permits concurrent high-throughput single-molecular …

Investigating single-molecule fluorescence spectral heterogeneity of rhodamines using high-throughput single-molecule spectroscopy

Y Zhang, Y Zhang, KH Song, W Lin, C Sun… - The journal of …, 2021 - ACS Publications
We experimentally investigated several intramolecular coordinate and environmental
changes as potential causes of single-molecule fluorescence spectral heterogeneities …

Switchable and Functional Fluorophores for Multidimensional Single-Molecule Localization Microscopy

Y Liu, MA Shahid, H Mao, J Chen… - … & Biomedical Imaging, 2023 - ACS Publications
Multidimensional single-molecule localization microscopy (mSMLM) represents a paradigm
shift in the realm of super-resolution microscopy techniques. It affords the simultaneous …