Mast cells in colorectal cancer tumour progression, angiogenesis, and lymphangiogenesis

X Liu, X Li, H Wei, Y Liu, N Li - Frontiers in Immunology, 2023 - frontiersin.org
The characteristics of the tumour cells, as well as how tumour cells interact with their
surroundings, affect the prognosis of cancer patients. The resident cells in the tumour …

SCF and IL-33 regulate mouse mast cell phenotypic and functional plasticity supporting a pro-inflammatory microenvironment

R Molfetta, M Lecce, ND Milito, E Putro… - Cell Death & …, 2023 - nature.com
Mast cells (MCs) are multifaceted innate immune cells often present in the tumor
microenvironment (TME). Several recent findings support their contribution to the transition …

Single-cell analysis unveils activation of mast cells in colorectal cancer microenvironment

Z Xie, L Niu, G Zheng, K Du, S Dai, R Li, H Dan… - Cell & Bioscience, 2023 - Springer
The role of mast cells (MCs) in colorectal cancer (CRC) remains unclear, and a
comprehensive single-cell study on CRC MCs has not been conducted. This study used a …

Identification of phenomic data in the pathogenesis of cancers of the gastrointestinal (GI) tract in the UK biobank

SH Tan, CA Guan, MA Bujang, WH Lai, PJ Voon… - Scientific reports, 2024 - nature.com
Gastrointestinal (GI) cancers account for a significant incidence and mortality rates of
cancers globally. Utilization of a phenomic data approach allows researchers to reveal the …

[HTML][HTML] Integrating scRNA-seq and bulk RNA-seq to characterize infiltrating cells in the colorectal cancer tumor microenvironment and construct molecular risk models

Q Wang, YF Zhang, CL Li, Y Wang, L Wu… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is a malignancy that is both highly lethal and heterogeneous.
Although the correlation between intra-tumoral genetic and functional heterogeneity and …

Identification of Colon Immune Cell Marker Genes Using Machine Learning Methods

Y Yang, Y Zhang, J Ren, K Feng, Z Li, T Huang, Y Cai - Life, 2023 - mdpi.com
Immune cell infiltration that occurs at the site of colon tumors influences the course of cancer.
Different immune cell compositions in the microenvironment lead to different immune …

[HTML][HTML] Comprehensive analysis and experimental verification of the mechanism of action of T cell-mediated tumor-killing related genes in Colon adenocarcinoma

J Chen, Z Wang, Q Zhu, S Ren, Y Xu, G Wang… - Translational …, 2024 - Elsevier
Background Colorectal cancer (CRC) is a prevalent malignancy of the digestive tract. A new
prognostic scoring model for colon adenocarcinoma (COAD) is developed in this study …

Identification of phenomic data in the pathogenesis of cancers of the gastrointestinal (GI) tract: A UK biobank data analysis

SH Tan, CA Guan, MA Bujang, WH Lai, PJ Voon… - 2023 - researchsquare.com
Purpose: Gastrointestinal (GI) cancers account for a significant incidence and mortality rates
of cancers globally. Utilization of a phenomic data approach allows researchers to reveal the …

SCF and IL-33 regulate mouse mast cell phenotypic and functional plasticity supporting a pro-inflammatory microenvironment

M Lecce, N Milito, E Putro, G Pietropaolo, C Marangio… - 2023 - researchsquare.com
Mast cells (MCs) are multifaceted innate immune cells often present in the tumor
microenvironment (TME). Several recent findings support their contribution in the transition …

Papel del microambiente Inflamatorio en la progresión del cáncer colorectal y la diabetes Tipo 2

D López Pérez - 2023 - digibug.ugr.es
The microenvironment is becoming critical to understand how different cells behave in
different contexts. The present thesis manuscript includes two chapters in which the …