Behavioral and neural subsystems of rodent exploration

SM Thompson, LE Berkowitz, BJ Clark - Learning and motivation, 2018 - Elsevier
Animals occupy territories in which resources such as food and shelter are often distributed
unevenly. While studies of exploratory behavior have typically involved the laboratory rodent …

The growing evidence for the importance of the otoliths in spatial memory

PF Smith - Frontiers in neural circuits, 2019 - frontiersin.org
Many studies have demonstrated that vestibular sensory input is important for spatial
learning and memory. However, it has been unclear what contributions the different parts of …

The effects of Lactobacillus reuteri microcapsules on radiation-induced brain injury by regulating the gut microenvironment

Y Zhang, J Hu, X Song, J Dai, Z Tang, G Huang… - Food & Function, 2023 - pubs.rsc.org
A radiation-induced brain injury (RIBI) is a major adverse event following radiotherapy of
malignant tumors. RIBI would affect cognitive function, leading to a series of complications …

Under or absent reporting of light stimuli in testing of anxiety-like behaviors in rodents: the need for standardization

LS Neuwirth, MT Verrengia… - Frontiers in molecular …, 2022 - frontiersin.org
Behavioral neuroscience tests such as the Light/Dark Test, the Open Field Test, the Elevated
Plus Maze Test, and the Three Chamber Social Interaction Test have become both essential …

Differential organization of open field behavior in mice following acute or chronic simulated GCR exposure

EA Schaeffer, AA Blackwell, JRO Oltmanns… - Behavioural Brain …, 2022 - Elsevier
Astronauts undertaking deep space travel will receive chronic exposure to the mixed
spectrum of particles that comprise Galactic Cosmic Radiation (GCR). Exposure to the …

Effects of acquired vestibular pathology on the organization of mouse exploratory behavior

MT Banovetz, RI Lake, AA Blackwell… - Experimental Brain …, 2021 - Springer
Rodent open field behavior is highly organized and occurs spontaneously in novel
environments. This organization is disrupted in mice with vestibular pathology, suggesting …

Spatial Disorientation Under Dark Conditions Across Development in an Alzheimer's Disease Mouse Model

AA Blackwell, FM Jodelka, RI Lake, ML Hastings… - Neuroscience, 2023 - Elsevier
Alzheimer's disease (AD) is associated with hippocampal neuropathology and cognitive
impairments, including wandering behavior or becoming lost in a familiar environment …

Organization of exploratory behavior under dark conditions in female and male rats

JRO Oltmanns, MH Lipton, N Adamczyk, RI Lake… - Behavioural …, 2021 - Elsevier
Sexually dimorphic performance has been observed across humans and rodents in many
spatial tasks. In general, these spatial tasks do not dissociate the use of environmental and …

Vestibular dysfunction and difficulty with driving: data from the 2001–2004 National Health and Nutrition Examination Surveys

EX Wei, Y Agrawal - Frontiers in neurology, 2017 - frontiersin.org
Background and objective There is growing understanding of the role of vestibular function
in spatial navigation and orientation. Individuals with vestibular dysfunction demonstrate …

Antisense oligonucleotide therapy rescues disruptions in organization of exploratory movements associated with Usher syndrome type 1C in mice

TN Donaldson, KT Jennings, LA Cherep… - Behavioural brain …, 2018 - Elsevier
Abstract Usher syndrome, Type 1C (USH1C) is an autosomal recessive inherited disorder in
which a mutation in the gene encoding harmonin is associated with multi-sensory deficits …