Glucocorticoids are among the most prescribed drugs worldwide for the treatment of
numerous immune and inflammatory disorders. They exert their actions by binding to the …

The glucocorticoid receptor (GR) is crucial for the effects of glucocorticoids (GCs). Several
polymorphisms of the GR are associated with altered sensitivity to GCs. For the ER22/23EK …

Objective: To develop consensus statements for the diagnosis and management of
corticosteroid insufficiency in critically ill adult patients. Participants: A multidisciplinary …

Natural and synthetic glucocorticoids (GCs) are widely employed in a number of
inflammatory, autoimmune and neoplastic diseases, and, despite the introduction of novel …

Glucocorticoids are involved in several responses triggered by a variety of environmental
and physiological stimuli. These hormones have a wide-range of regulatory effects in …

Cortisol is involved in many physiological processes, including immunosuppressive and anti-
inflammatory actions, and therefore cortisol and its synthetic analogs are widely used to treat …

Glucocorticoids (GCs) are steroid hormones that influence several physiologic functions and
are among the most frequently prescribed drugs worldwide. Resistance to GCs has been …

Alcoholic hepatitis is a major health and economic burden worldwide. Glucocorticoids (GCs)
are the only first-line drugs recommended to treat severe alcoholic hepatitis (sAH), with …

In recent years, the incidence of inflammatory bowel disease (IBD) has been on the rise,
extending to countries where it was infrequent in the past. As a result, the gap between high …

Background Glucocorticoids (GCs) are used in moderate-to-severe inflammatory bowel
diseases (IBD) but their effect is often unpredictable. Aim To determine the influence of 4 …