Phage display technology, which is based on the presentation of peptide sequences on the
surface of bacteriophage virions, was developed over 30 years ago. Improvements in phage …

Monoclonal antibodies (mAbs) have become one of the most important classes of
biopharmaceutical products, and they continue to dominate the universe of …

Antibody display technologies enable the successful isolation of antigen-specific antibodies
with therapeutic potential. The key feature that facilitates the selection of an antibody with …

In crossing a heath, suppose... I had found a watch upon the ground, and it should be
inquired how the watch happened to be in that place....[T] he inference, we think, is …

To by-pass hybridoma technology and animal immunization, we are trying to build
antibodies in bacteria by mimicking features of immune selection1. Recently we used fd …

We have mimicked features of immune selection to make human antibodies in bacteria.
Diverse libraries of immunoglobulin heavy (VH) and light (V κ and V λ chain variable (V) …

Antibody fragments of predetermined binding specificity have recently been constructed
from repertoires of antibody V genes, bypassing hybridoma technology and even …

▪ Abstract Cys2His2 zinc fingers are one of the most common DNA-binding motifs found in
eukaryotic transcription factors. These proteins typically contain several fingers that make …

A phagemid system was developed for the monovalent display of combinatorial antibody
Fab libraries on the surface of filamentous phage M13. Fab fragments were fused to the …

The function and activity of a protein are often modulated by other proteins with which it
interacts. This review is intended as a practical guide to the analysis of such protein-protein …