Glutathione (GSH) is an important member of cellular antioxidative system. In cancer cells, a
high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) …

Poor water solubility, off-target toxicity, and small therapeutic window are among major
obstacles for the development of drug products. Redox-responsive drug delivery …

Despite enormous advancements in the field of oncology, the innocuous and effectual
treatment of various types of malignancies remained a colossal challenge. The conventional …

Gene therapy provides a promising strategy for curing monogenetic disorders and complex
diseases. However, there are challenges associated with the use of viral delivery vectors …

Gene therapy encompasses the transfer of exogenous genetic materials into the patient's
target cells to treat or prevent diseases. Nevertheless, the transfer of genetic material into …

Amphiphilic Janus dendrimers are arrangements containing both hydrophilic and
hydrophobic units, capable of forming ordered aggregates by intermolecular noncovalent …

The design of pH-sensitive supramolecular drug delivery systems for efficient antineoplastic
drug delivery remains a huge challenge. Herein, we describe the development of pH …

Due to the weak interfacial bonding caused by the poor wettability and adsorption between
carbon fibers (CFs) and matrix, CFs cannot fully exert their excellent mechanical properties …

Combination therapy involving chemotherapeutic drugs and genes is emerging as a
promising strategy to provide a synergistic therapeutic effect, to overcome drug resistance …

Background Even with the advancement in the areas of cancer nanotechnology, prostate
cancer still poses a major threat to men's health. Nanomaterials and nanomaterial-derived …