Stress and cancer: mechanisms, significance and future directions
A Eckerling, I Ricon-Becker, L Sorski… - Nature Reviews …, 2021 - nature.com
The notion that stress and cancer are interlinked has dominated lay discourse for decades.
More recent animal studies indicate that stress can substantially facilitate cancer …
More recent animal studies indicate that stress can substantially facilitate cancer …
Aspects of the tumor microenvironment involved in immune resistance and drug resistance
K Khalaf, D Hana, JTT Chou, C Singh… - Frontiers in …, 2021 - frontiersin.org
The tumor microenvironment (TME) is a complex and ever-changing “rogue organ”
composed of its own blood supply, lymphatic and nervous systems, stroma, immune cells …
composed of its own blood supply, lymphatic and nervous systems, stroma, immune cells …
The impact of psychosocial stress and stress management on immune responses in patients with cancer
MH Antoni, FS Dhabhar - Cancer, 2019 - Wiley Online Library
The range of psychosocial stress factors/processes (eg, chronic stress, distress states,
coping, social adversity) were reviewed as they relate to immune variables in cancer along …
coping, social adversity) were reviewed as they relate to immune variables in cancer along …
Tumor microenvironment of hepatocellular carcinoma: challenges and opportunities for new treatment options
Z Sas, E Cendrowicz, I Weinhäuser… - International Journal of …, 2022 - mdpi.com
The prevalence of liver cancer is constantly rising, with increasing incidence and mortality in
Europe and the USA in recent decades. Among the different subtypes of liver cancers …
Europe and the USA in recent decades. Among the different subtypes of liver cancers …
Tumor innervation: peripheral nerves take control of the tumor microenvironment
In recent decades, cancer research has expanded exponentially beyond the study of
abnormally dividing cells to include complex and extensive heterotypic interactions between …
abnormally dividing cells to include complex and extensive heterotypic interactions between …
Exploiting the critical perioperative period to improve long-term cancer outcomes
M Horowitz, E Neeman, E Sharon… - Nature reviews Clinical …, 2015 - nature.com
Evidence suggests that the perioperative period and the excision of the primary tumour can
promote the development of metastases—the main cause of cancer-related mortality. This …
promote the development of metastases—the main cause of cancer-related mortality. This …
The sympathetic nervous system induces a metastatic switch in primary breast cancer
EK Sloan, SJ Priceman, BF Cox, S Yu, MA Pimentel… - Cancer research, 2010 - AACR
Metastasis to distant tissues is the chief driver of breast cancer–related mortality, but little is
known about the systemic physiologic dynamics that regulate this process. To investigate …
known about the systemic physiologic dynamics that regulate this process. To investigate …
Perioperative COX-2 and β-adrenergic blockade improves metastatic biomarkers in breast cancer patients in a phase-II randomized trial
L Shaashua, M Shabat-Simon, R Haldar… - Clinical Cancer …, 2017 - AACR
Purpose: Translational studies suggest that excess perioperative release of catecholamines
and prostaglandins may facilitate metastasis and reduce disease-free survival. This trial …
and prostaglandins may facilitate metastasis and reduce disease-free survival. This trial …
Epidural anesthesia–analgesia and recurrence-free survival after lung cancer surgery: a randomized trial
ZZ Xu, HJ Li, MH Li, SM Huang, X Li, QH Liu… - …, 2021 - ingentaconnect.com
Background: Regional anesthesia and analgesia reduce the stress response to surgery and
decrease the need for volatile anesthesia and opioids, thereby preserving cancer-specific …
decrease the need for volatile anesthesia and opioids, thereby preserving cancer-specific …
The influence of bio-behavioural factors on tumour biology: pathways and mechanisms
Epidemiological studies indicate that stress, chronic depression and lack of social support
might serve as risk factors for cancer development and progression. Recent cellular and …
might serve as risk factors for cancer development and progression. Recent cellular and …