Streptococcus pneumoniae (Spn) is a major public health problem, as it is a main cause of
otitis media, community-acquired pneumonia, bacteremia, sepsis, and meningitis. Acute …

The neutrophil, a short-lived effector leukocyte of the innate immune system best known for
its proteases and other degradative cargo, has unique, reciprocal physiological interactions …

Environmental microbial triggers shape the development and functionality of the immune
system. Alveolar macrophages (AMs), tissue-resident macrophages of the lungs, are in …

This study investigates how specific members of the lung microbiome influence the early
immune response to infection. Prevotella species are a major component of the endogenous …

The limited reserves of neutrophils are implicated in the susceptibility to infection in
neonates, however the regulation of neutrophil kinetics in infections in early life remains …

Inflammatory responses contribute to host defense against harmful organisms and
allergens, whereas a failure of immune tolerance can cause chronic inflammation including …

This study is a successor of our previous work concerning changes in the chemokine profile
in infection that are associated with different SARS-CoV-2 genetic variants. The goal of our …

Bacterial and viral pathogens are predominant causes of pulmonary infections and
complications. Morbidity and mortality from these infections is increased in populations that …

Streptococcus pneumoniae (Spn) is the primary agent of community-acquired pneumonia.
Neutrophils are innate immune cells that are essential for bacterial clearance during …

The braking mechanisms to protect the host from tissue damage and inflammatory disease
caused by an overexuberant immune response are common in many T cell subsets …