Reactive oxygen species (ROS) play a critical role in defining the functional competence of
human spermatozoa. When generated in moderate amounts, ROS promote sperm …

Oxidative stress plays a major role in the life and death of mammalian spermatozoa. These
gametes are professional generators of reactive oxygen species (ROS), which appear to …

Male and female germ lines are vulnerable to oxidative stress. In spermatozoa, such stress
triggers a lipid peroxidation cascade that culminates in the generation of electrophilic lipid …

This article addresses the importance of oxidative processes in both the generation of
functional gametes and the aetiology of defective sperm function. Functionally, sperm …

Spermatozoa are highly vulnerable to oxidative attack because they lack significant
antioxidant protection due to the limited volume and restricted distribution of cytoplasmic …

Reactive oxygen species (ROS) generated at low levels during mitochondrial respiration
have key roles in several signaling pathways. Oxidative stress (OS) arises when the …

Oxidative stress occurs when the levels of reactive oxygen species (ROS) overcome the
antioxidant defenses of the organism, jeopardizing several biological functions, including …

In brief Many aspects of the reproductive process are impacted by oxidative stress. This
article summarizes the chemical nature of reactive oxygen species and their role in both the …

In brief This review focuses on the enzymatic antioxidant mechanisms to fight oxidative
stress by spermatozoa, highlighting the differences among mammalian species. We discuss …

Despite the high prevalence of male infertility, very little is known about its etiology. In recent
years however, advances in gene sequencing technology have enabled us to identify a …