Molecular mechanisms of oxidative stress in asthma

C Michaeloudes, H Abubakar-Waziri, R Lakhdar… - Molecular aspects of …, 2022 - Elsevier
The lungs are exposed to reactive oxygen species oxygen (ROS) produced as a result of
inhalation of oxygen, as well as smoke and other air pollutants. Cell metabolism and the …

Airway remodeling in asthma

KP Hough, ML Curtiss, TJ Blain, RM Liu, J Trevor… - Frontiers in …, 2020 - frontiersin.org
Asthma is an inflammatory disease of the airways that may result from exposure to allergens
or other environmental irritants, resulting in bronchoconstriction, wheezing, and shortness of …

European Respiratory Society guidelines for the diagnosis of asthma in adults

R Louis, I Satia, I Ojanguren, F Schleich… - European …, 2022 - Eur Respiratory Soc
Although asthma is very common, affecting 5–10% of the population, the diagnosis of
asthma in adults remains a challenge in the real world, which results in both over-and under …

Exploring the relevance and extent of small airways dysfunction in asthma (ATLANTIS): baseline data from a prospective cohort study

DS Postma, C Brightling, S Baldi… - The Lancet …, 2019 - thelancet.com
Background Small airways dysfunction (SAD) is well recognised in asthma, yet its role in the
severity and control of asthma is unclear. This study aimed to assess which combination of …

Airway remodeling heterogeneity in asthma and its relationship to disease outcomes

A Hsieh, N Assadinia, TL Hackett - Frontiers in physiology, 2023 - frontiersin.org
Asthma affects an estimated 262 million people worldwide and caused over 461,000 deaths
in 2019. The disease is characterized by chronic airway inflammation, reversible …

Radiomics in lung diseases imaging: state-of-the-art for clinicians

AN Frix, F Cousin, T Refaee, F Bottari… - Journal of Personalized …, 2021 - mdpi.com
Artificial intelligence (AI) has increasingly been serving the field of radiology over the last 50
years. As modern medicine is evolving towards precision medicine, offering personalized …

Prenatal fine particulate exposure and early childhood asthma: effect of maternal stress and fetal sex

A Lee, HHL Hsu, YHM Chiu, S Bose, MJ Rosa… - Journal of Allergy and …, 2018 - Elsevier
Background The impact of prenatal ambient air pollution on child asthma may be modified
by maternal stress, child sex, and exposure dose and timing. Objective We prospectively …

Multifractal analysis of temporal and spatial characteristics of earthquakes in Eurasian seismic belt

J Chen, L Wen, C Bi, Z Liu, X Liu, L Yin… - Open Geosciences, 2023 - degruyter.com
Seismic activity has complexity and randomness, and its temporal and spatial distribution
has complexity, stage, level, and inheritance. The study of the temporal and spatial …

Childhood asthma: pathogenesis and phenotypes

MW Pijnenburg, U Frey, JC De Jongste… - European Respiratory …, 2022 - Eur Respiratory Soc
In the pathogenesis of asthma in children there is a pivotal role for a type 2 inflammatory
response to early life exposures or events. Interactions between infections, atopy, genetic …

[HTML][HTML] Relationship between lung function and quantitative computed tomographic parameters of airway remodeling, air trapping, and emphysema in patients with …

RA Hartley, BL Barker, C Newby, M Pakkal… - Journal of Allergy and …, 2016 - Elsevier
Background There is a paucity of studies comparing asthma and chronic obstructive
pulmonary disease (COPD) based on thoracic quantitative computed tomographic (QCT) …