Skin wound repair is a multistage process involving multiple cellular and molecular
interactions, which modulate the cell behaviors and dynamic remodeling of extracellular …

The role and importance of mechanical properties of cells and tissues in cellular function,
development and disease has widely been acknowledged, however standard techniques …

The way in which cells coordinate their behaviours during various biological processes,
including morphogenesis, cancer progression and tissue remodelling, largely depends on …

Cutaneous wound healing in adult mammals is a complex multi-step process involving
overlapping stages of blood clot formation, inflammation, re-epithelialization, granulation …

Collective cell migration is a key driver of embryonic development, wound healing, and
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …

The epithelial-to-mesenchymal transition (EMT) and the unjamming transition (UJT) each
comprises a gateway to cellular migration, plasticity and remodeling, but the extent to which …

Cell adhesion is essential in cell communication and regulation, and is of fundamental
importance in the development and maintenance of tissues. The mechanical interactions …

Chemical and physical properties of the environment control cell proliferation, differentiation,
or apoptosis in the long term. However, to be able to move and migrate through a complex …

Evidence from physical sciences in oncology increasingly suggests that the interplay
between the biophysical tumor microenvironment and genetic regulation has significant …

E-cadherin is a major homophilic cell-cell adhesion molecule that inhibits motility of
individual cells on matrix. However, its contribution to migration of cells through cell-rich …