The human eye is a sophisticated organ with distinctive anatomy and physiology that
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …

There is a growing interest in the development of lipid-based nanocarriers for multiple
purposes, including the recent increase of these nanocarriers as vaccine components …

Cancer therapy is a significant challenge due to insufficient drug delivery to the cancer cells
and non-selective killing of healthy cells by most chemotherapy agents. Nano-formulations …

The use of messenger RNA (mRNA) in gene therapy is increasing in recent years, due to its
unique features compared to plasmid DNA: Transient expression, no need to enter into the …

The proposal of gene therapy to tackle cancer development has been instrumental for the
development of novel approaches and strategies to fight this disease, but the efficacy of the …

Delivery of genes, including plasmid DNAs, short interfering RNAs (siRNAs), and
messenger RNAs (mRNAs), using artificial non-viral nanotherapeutics is a promising …

Lipid‐based nanoparticles have emerged as a clinically viable platform technology to
deliver nucleic acids for a wide range of healthcare applications. Within this scope, one of …

Background Fabry disease, an inherited lysosomal storage disorder, causes multi-organ
pathology resulting in substantial morbidity and a reduced life expectancy. Although Fabry …

With the rapid development of biopharmaceuticals and the outbreak of COVID-19, the world
has ushered in a frenzy to develop gene therapy. Therefore, therapeutic genes have …

Microfluidics is an emerging technology that can be employed as a powerful tool for
designing lipid nano-microsized structures for biological applications. Those lipid structures …