Schistosoma genomics: new perspectives on schistosome biology and host-parasite interaction

ZG Han, PJ Brindley, SY Wang… - Annual review of …, 2009 - annualreviews.org
Schistosomiasis, caused mainly by Schistosoma japonicum, S. mansoni, and S.
hematobium, remains one of the most prevalent and serious parasitic diseases worldwide …

Structural and functional evolution of the translocator protein (18 kDa)

J Fan, P Lindemann, M GJ Feuilloley… - Current molecular …, 2012 - ingentaconnect.com
Translocator proteins (TSPO) are the products of a family of genes that is evolutionarily
conserved from bacteria to humans and expressed in most mammalian tissues and cells …

Transcriptome analysis of the acoelomate human parasite Schistosoma mansoni

S Verjovski-Almeida, R DeMarco, EAL Martins… - Nature …, 2003 - nature.com
Schistosoma mansoni is the primary causative agent of schistosomiasis, which affects 200
million individuals in 74 countries. We generated 163,000 expressed-sequence tags (ESTs) …

Evolutionary and biomedical implications of a Schistosoma japonicum complementary DNA resource

W Hu, Q Yan, DK Shen, F Liu, ZD Zhu, HD Song… - Nature …, 2003 - nature.com
Schistosoma japonicum causes schistosomiasis in humans and livestock in the Asia-Pacific
region. Knowledge of the genome of this parasite should improve understanding of …

Using RNA interference to manipulate endogenous gene expression in Schistosoma mansoni sporocysts

JP Boyle, XJ Wu, CB Shoemaker, TP Yoshino - Molecular and biochemical …, 2003 - Elsevier
Direct assessments of gene function in parasitic flatworms have been hampered by the lack
of effective tools to alter gene expression. The aim of the present study was to use RNA …

An oligonucleotide microarray for transcriptome analysis of Schistosoma mansoni and its application/use to investigate gender-associated gene expression

JM Fitzpatrick, DA Johnston, GW Williams… - Molecular and …, 2005 - Elsevier
Global profiling transcriptomes of parasitic helminths offers the potential to simultaneously
identify co-ordinately expressed genes, novel genetic programs and uniquely utilized …

Helminth vaccines: from mining genomic information for vaccine targets to systems used for protein expression

JP Dalton, PJ Brindley, DP Knox, CP Brady… - International journal for …, 2003 - Elsevier
The control of helminth diseases of people and livestock continues to rely on the widespread
use of anti-helminthic drugs. However, concerns with the appearance of drug resistant …

Onchocerca volvulus Glycolytic Enzyme Fructose-1,6-Bisphosphate Aldolase as a Target for a Protective Immune Response in Humans

JS McCarthy, M Wieseman, J Tropea… - Infection and …, 2002 - Am Soc Microbiol
To identify potential vaccine candidates for the prevention of infection with the filarial
nematode Onchocerca volvulus, we screened an O. volvulus L3 stage cDNA library with …

Schistosome transcriptomes: new insights into the parasite and schistosomiasis

W Hu, PJ Brindley, DP McManus, Z Feng… - Trends in Molecular …, 2004 - cell.com
Schistosomiasis is one of the most serious parasitic diseases. More than 250 million people
are infected with schistosomes in the tropics or subtropics. The parasitic flukes have some …

Analysis of grape ESTs: global gene expression patterns in leaf and berry

E Ablett, G Seaton, K Scott, D Shelton, MW Graham… - Plant Science, 2000 - Elsevier
Analysis of 2479 ESTs from Vitis vinifera berry tissue and 2438 from leaf revealed that 1% of
the ESTs match to known Vitis proteins, 72% to plant proteins, 11% to non-plant, and 16 …