Colon cancer poses a complex and substantial global health challenge, necessitating
innovative therapeutic approaches. Chalcones, a versatile class of compounds with diverse …

Inflammation is a physiological process that involves a variety of inflammatory mediators
such as PGE2, Nitric oxides, PLA2 etc., blocking these mediators could be helpful in …

Plant secondary metabolites such as flavonoids demonstrate high degrees of antioxidant,
anti-inflammatory, and anticancer activities. Among flavonoids, quercetin plays an important …

The combination of natural products with standard chemotherapeutic agents offers a
promising strategy to enhance the efficacy or reduce the side effects of standard …

The potential of the 4, 6-diphenyl-3, 4-dihydropyrimidine-2 (1 H)-thione (abbreviated as
KKII5) and (E)-N′-benzylidenehydrazinecarbothiohydrazide (abbreviated as DKI5) …

Farnesylated chalcones were favored by researchers due to their different biological
activities. However, only five naturally occurring farnesylated chalcones were described in …

Phytochemical investigation of the methanol extract of the seeds of P. harmala afforded two
new alkaloids namely, 1‑hydroxy-1-norharmaline (4) and 7-norharmalacidine hydrochloride …

Two novel copper (II) complexes [Cu (TFP)(Gly) Cl]⋅ 2H2O complex (1) and [Cu (TFP)(His)
Cl]⋅ 2H2O complex (2) are synthesized, where TFP stands for trifluropromazine, Gly …

In this study, 2 chalcone analogues were synthesized and assessed through in silico and
experimental methods for their potential to inhibit the lipoxygenase enzyme, which plays a …

Dear Colleagues, Dr. Robert Verpoorte, Emeritus Professor at the Institute of Biology of
Leiden University is among the most recognized world-wide experts in natural product …