Artificial intelligence in cancer target identification and drug discovery

Y You, X Lai, Y Pan, H Zheng, J Vera, S Liu… - … and Targeted Therapy, 2022 - nature.com
Artificial intelligence is an advanced method to identify novel anticancer targets and discover
novel drugs from biology networks because the networks can effectively preserve and …

Hospital networks and the dispersal of hospital-acquired pathogens by patient transfer

T Donker, J Wallinga, R Slack, H Grundmann - PloS one, 2012 - journals.plos.org
Hospital-acquired infections (HAI) are often seen as preventable incidents that result from
unsafe practices or poor hospital hygiene. This however ignores the fact that transmissibility …

Analysis of a summary network of co-infection in humans reveals that parasites interact most via shared resources

EC Griffiths, AB Pedersen… - Proceedings of the …, 2014 - royalsocietypublishing.org
Simultaneous infection by multiple parasite species (viruses, bacteria, helminths, protozoa
or fungi) is commonplace. Most reports show co-infected humans to have worse health than …

Model of complex networks based on citation dynamics

L Šubelj, M Bajec - Proceedings of the 22nd international conference on …, 2013 - dl.acm.org
Complex networks of real-world systems are believed to be controlled by common
phenomena, producing structures far from regular or random. These include scale-free …

Computational modeling of allosteric regulation in the hsp90 chaperones: a statistical ensemble analysis of protein structure networks and allosteric communications

K Blacklock, GM Verkhivker - PLoS computational biology, 2014 - journals.plos.org
A fundamental role of the Hsp90 chaperone in regulating functional activity of diverse
protein clients is essential for the integrity of signaling networks. In this work we have …

Dynamic modular architecture of protein-protein interaction networks beyond the dichotomy of 'date'and 'party'hubs

X Chang, T Xu, Y Li, K Wang - Scientific reports, 2013 - nature.com
The protein-protein interaction (PPI) networks are dynamically organized as modules and
are typically described by hub dichotomy:'party'hubs act as intramodule hubs and are …

Dynamics of inter-farm transmission of highly pathogenic avian influenza H5N6 integrating vehicle movements and phylogenetic information

DS Yoo, B Chun, Y Kim, KN Lee, OK Moon - Scientific Reports, 2021 - nature.com
Highly pathogenic avian influenza (HPAI) in poultry holdings commonly spreads through
animal trade, and poultry production and health-associated vehicle (PPHaV) movement. To …

Examining indicators of complex network vulnerability across diverse attack scenarios

AF Al Musawi, S Roy, P Ghosh - Scientific Reports, 2023 - nature.com
Complex networks capture the structure, dynamics, and relationships among entities in real-
world networked systems, encompassing domains like communications, society, chemistry …

CompNet: a GUI based tool for comparison of multiple biological interaction networks

BK Kuntal, A Dutta, SS Mande - BMC bioinformatics, 2016 - Springer
Background Network visualization and analysis tools aid in better understanding of complex
biological systems. Furthermore, to understand the differences in behaviour of system (s) …

Mild traumatic brain injury history is associated with lower brain network resilience in soldiers

JR Powell, JB Hopfinger, KS Giovanello… - Brain …, 2023 - academic.oup.com
Abstract Special Operations Forces combat soldiers sustain frequent blast and blunt
neurotrauma, most often classified as mild traumatic brain injuries. Exposure to repetitive …