Hippocampus and its involvement in Alzheimer's disease: a review

YL Rao, B Ganaraja, BV Murlimanju, T Joy… - 3 Biotech, 2022 - Springer
Hippocampus is the significant component of the limbic lobe, which is further subdivided into
the dentate gyrus and parts of Cornu Ammonis. It is the crucial region for learning and …

A review on Alzheimer's disease classification from normal controls and mild cognitive impairment using structural MR images

N Garg, MS Choudhry, RM Bodade - Journal of neuroscience methods, 2023 - Elsevier
Alzheimer's disease (AD) is an irreversible neurodegenerative brain disorder that degrades
the memory and cognitive ability in elderly people. The main reason for memory loss and …

An integrative collaborative care model for people with mental illness and physical comorbidities

C Ee, J Lake, J Firth, F Hargraves… - International Journal of …, 2020 - Springer
Background Many individuals with mental health problems have comorbid physical
conditions, or may present with substance/alcohol misuse or abuse issues. This results in …

Deep spatial-temporal feature fusion from adaptive dynamic functional connectivity for MCI identification

Y Li, J Liu, Z Tang, B Lei - IEEE Transactions on Medical …, 2020 - ieeexplore.ieee.org
Dynamic functional connectivity (dFC) analysis using resting-state functional Magnetic
Resonance Imaging (rs-fMRI) is currently an advanced technique for capturing the dynamic …

The hippocampus associated GABAergic neural network impairment in early-stage of Alzheimer's disease

Y Tang, Y Yan, J Mao, J Ni, H Qing - Ageing Research Reviews, 2023 - Elsevier
Alzheimer's disease (AD) is the commonest neurodegenerative disease with slow
progression. Pieces of evidence suggest that the GABAergic system is impaired in the early …

Virtual adversarial training-based deep feature aggregation network from dynamic effective connectivity for MCI identification

Y Li, J Liu, Y Jiang, Y Liu, B Lei - IEEE transactions on medical …, 2021 - ieeexplore.ieee.org
Dynamic functional connectivity (dFC) network inferred from resting-state fMRI reveals
macroscopic dynamic neural activity patterns for brain disease identification. However, dFC …

Obesity during preclinical Alzheimer's disease development exacerbates brain metabolic decline

T Anderson, S Sharma, MA Kelberman… - Journal of …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is the most common form of dementia. Obesity in middle age
increases AD risk and severity, which is alarming given that obesity prevalence peaks at …

[HTML][HTML] Polygonatum sibiricum polysaccharides improve cognitive function in D-galactose-induced aging mice by regulating the microbiota-gut-brain axis

Z Liu, S Fayyaz, D Zhao, Z Yi, J Huang, R Zhou… - Journal of Functional …, 2023 - Elsevier
Anti-aging has attracted worldwide attention. Polygonatum sibiricum polysaccharide (PSP),
as the main component of Polygonatum sibiricum, has shown good anti-aging activity by …

Protection of MCC950 against Alzheimer's disease via inhibiting neuronal pyroptosis in SAMP8 mice

J Li, L Zhuang, X Luo, J Liang, E Sun, Y He - Experimental Brain Research, 2020 - Springer
Neuronal dysfunction and loss are thought to be one of the causes of cognitive impairment
in Alzheimer's disease (AD), but the specific mechanism of neuronal loss in the …

Benign regulation of the gut microbiota: The possible mechanism through which the beneficial effects of manual acupuncture on cognitive ability and intestinal …

X Hao, N Ding, Y Zhang, Y Yang, Y Zhao… - Frontiers in …, 2022 - frontiersin.org
Background Gut microbiota dysbiosis and intestinal barrier injury play vital roles in
Alzheimer's disease (AD) onset and development. Our previous studies have demonstrated …