Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …

Acute inflammatory lesions of the placenta consist of diffuse infiltration of neutrophils at
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and …

Preterm birth is associated with 5 to 18% of pregnancies and is a leading cause of infant
morbidity and mortality. Spontaneous preterm labor, a syndrome caused by multiple …

More than 135 million births occur each year; yet, the molecular underpinnings of human
parturition in gestational tissues, and in particular the placenta, are still poorly understood …

Problem Inflammation and infection play a major role in preterm birth. The purpose of this
study was to (i) determine the prevalence and clinical significance of sterile intra‐amniotic …

Oxidative stress (OS), an imbalance between free radical generation and antioxidant
defence, is recognized as a key factor in the pathogenesis of adverse pregnancy outcomes …

An improved mechanistic understanding of the adaptational processes mounted during
mammalian reproduction is emerging. Intricate pathways occurring at the fetomaternal …

Oxidative stress (OS), a state characterized by an imbalance between pro-oxidant molecules
including reactive oxygen and nitrogen species, and antioxidant defenses, has been …

The implicit paradigm that has governed the study and clinical management of preterm
labour is that term and preterm parturition are the same processes, except for the gestational …

Inflammation is a process by which tissues respond to various insults. It is characterized by
upregulation of chemokines, cytokines, and pattern recognition receptors that sense …