Arynes are among the most active organic intermediates and have found numerous
applications in expeditious preparation of substituted arenes. In the past 20 years, chemists …

Additions of homoelement-element and heteroelementelement linkages to unsaturated
substrates catalyzed by the platinum group metals constitute synthetically highly versatile …

Arynes are neutral intermediates in which two adjacent atoms of an aromatic ring lack
substituents, thus leaving two atomic orbitals (perpendicular to the aromatic x system) to …

A palladium-catalyzed domino aminopalladation/CH functionalization sequence has been
developed, and provides access to functionalized phenanthridines and isoquinolines. The …

A wide variety of 3-halospiro [4.5] trienones are readily prepared in good to excellent yields
by the intramolecular ipso-halocyclization of 4-(p-methoxyaryl)-1-alkynes under mild …

An efficient, mild, transition-metal-free method has been developed for the intermolecular C−
N σ-bond addition of amides and S− N σ-bond addition of sulfinamides to arynes to form one …

It is well known that the high strain created by the formal triple bond of arynes makes these
compounds powerful electrophiles.[1] The addition of a nucleophile X to benzyne leads to …

The Pd-catalyzed annulation of arynes by 2-halobiaryls and related vinylic halides provides
a very efficient, high yielding synthesis of polycyclic aromatic and heteroaromatic …

A useful synthetic method for building up multisubstituted arenes of structural complexity and
diversity by use of aromatic reactive intermediates is described. Regardless of the transient …

The first Pd (0)-catalyzed carbene insertion into Si–Si and Sn–Sn bonds has been realized
by using N-tosylhydrazones as the carbene precursors. Geminal bis (silane) and geminal …