Detergents are indispensable in the isolation of integral membrane proteins from biological
membranes to study their intrinsic structural and functional properties. Solubilization …

The aquaporins (AQPs) are a family of small membrane-spanning proteins (monomer size∼
30 kDa) that are expressed at plasma membranes in many cells types involved in fluid …

Understanding the mechanisms of action of membrane proteins requires the elucidation of
their structures to high resolution. The critical step in accomplishing this by x-ray …

Publisher Summary The reconstitution of membrane proteins into liposomes is a powerful
tool that can be used to identify the mechanism of the action of membrane proteins. The …

Biochim~ic~a Page 1 ELSEVIER Biochimica et Biophysica Acta 1231 (1995) 223-246
Biochim~ic~a et Biophysica A~ta Review Reconstitution of membrane proteins into liposomes …

Atomic force microscopy (AFM) is part of a range of emerging microscopic methods for
biologists which offer the magnification range of both the light and electron microscope, but …

The plasma membrane is of central importance for defining the closed volume of cells in
contradistinction to the extracellular environment. The plasma membrane not only serves as …

LIGHT absorption by the visual pigment rhodopsin1, 2 triggers, through G-protein coupling,
a cascade of events in the outer segment of the rod cell of the vertebrate retina that results in …

Determination of the structure of integral membrane proteins is a challenging task that is
essential to understand how fundamental biological processes (such as photosynthesis …

The G-protein coupled receptors form a large and diverse multi-gene superfamily with many
important physiological functions. As such, they have become important targets in …