The transforming growth factor β (TGF-β) family controls many fundamental aspects of
cellular behavior. With advances in the molecular details of the TGF-β signaling cascade …

Smad transcription factors lie at the core of one of the most versatile cytokine signaling
pathways in metazoan biology—the transforming growth factor-β (TGFβ) pathway. Recent …

Several long noncoding RNAs (lncRNA) are abrogated in cancer but their precise
contributions to oncogenesis are still emerging. Here we report that the lncRNA MALAT1 is …

The TGF-β family comprises many structurally related differentiation factors that act through
a heteromeric receptor complex at the cell surface and an intracellular signal transducing …

Transforming growth factor β (TGFβ) pathways are implicated in metazoan development,
adult homeostasis and disease. TGFβ ligands signal via receptor serine/threonine kinases …

The canonical WNT/β-catenin signaling pathway governs a myriad of biological processes
underlying the development and maintenance of adult tissue homeostasis, including …

The BMP and Wnt/β-catenin signaling pathways cooperatively regulate osteoblast
differentiation and bone formation. Although BMP signaling regulates gene expression of …

Lymphoid enhancer factor/T cell factor proteins (LEF/TCFs) mediate Wnt signals in the
nucleus by recruiting β-catenin and its co-activators to Wnt response elements (WREs) of …

The process of implantation, necessary for all viviparous birth, consists of tightly regulated
events, including apposition of the blastocyst, attachment to the uterine lumen, and …

Abstract Bone morphogenetic protein 9 (BMP‐9) is a member of the transforming growth
factor (TGF)‐β/BMP superfamily, and we have demonstrated that it is one of the most potent …