The HtrA family of chaperones and serine proteases is important for regulating stress
responses and controlling protein quality in the periplasm of bacteria. HtrA is also …

Signal peptide-driven secretion of precursor proteins directs polypeptides across the plasma
membrane of bacteria. Two pathways, Sec-and SRP-dependent, converge at the SecYEG …

Being the principal causative agent of bacterial pneumonia, otitis media, meningitis and
septicemia, the bacterium Streptococcus pneumoniae is a major global health problem. To …

S treptococcus pneumoniae is an oval‐shaped G ram‐positive coccus that lives in intimate
association with its human host, both as a commensal and pathogen. The seriousness of …

Control and manipulation of bacterial populations requires an understanding of the factors
that govern growth, division, and antibiotic action. Fluorescent and chemically reactive small …

The HtrA proteases degrade damaged proteins and thus control the quality of proteins and
protect cells against the consequences of various stresses; they also recognize specific …

The formation of lateral microdomains is emerging as a central organizing principle in
bacterial membranes. These microdomains are targets of antibiotic development and have …

Sortase-assembled pili contribute to virulence in many Gram-positive bacteria. In
Enterococcus faecalis, the endocarditis and biofilm-associated pilus (Ebp) is polymerized on …

Bacterial cell shapes are manifestations of programs carried out by multi‐protein machines
that synthesize and remodel the resilient peptidoglycan (PG) mesh and other polymers …

The relative localization patterns of class B penicillin‐binding proteins Pbp2x and Pbp2b
were used as positional indicators of septal and peripheral (side‐wall‐like) peptidoglycan …