Anticancer Asparaginases: perspectives in using filamentous Fungi as cell factories

PHD Garcia, TA Costa-Silva, MM Gómez, FJ Contesini… - Catalysts, 2023 - mdpi.com
The enzyme L-asparaginase (L-asparagine amidohydrolase) catalyzes the breakdown of L-
asparagine into aspartate and ammonia, which leads to an anti-neoplastic activity stemming …

Production of cold-active pectinases by three novel Cladosporium species isolated from Egypt and application of the most active enzyme

AM Moharram, ANA Zohri, AEL Hesham… - Scientific Reports, 2022 - nature.com
Cladosporium parasphaerospermum, Cladosporium chlamydosporigenum, and
Cladosporium compactisporum have all been discovered and characterized as new …

In silico and biochemical analysis on a newly isolated Trichoderma asperellum L-asparaginase

YM Elsaba, WH Salama, ERS Soliman - Biocatalysis and Agricultural …, 2022 - Elsevier
Microbial l-asparaginase enzyme has been considered as a good source of potential
anticancer drugs. The enzyme purified from different microbes has been shown different …

Remarkable improvement of levansucrase production from a newly isolated Aspergillus niger MK788296 strain using agro-industrial wastes through statistical …

NH Elzairy, FA Mostafa, WAA Wahab… - Egyptian …, 2023 - journals.lww.com
Materials and methods A potent fungal producer of LS was isolated from an Egyptian soil
sample that was collected from Giza Governorate at a depth of 5 cm and identified based on …

The nutritional and cultural conditions in shake flask culture for improved production of L-Asparaginase from endophytic fungus Fusarium sp. LCJ324: A sequential …

E Udayan, A Kathiravan… - Italian Journal of …, 2023 - italianmycology.unibo.it
L-Asparaginase has a greater demand due to its potential application in the food industry as
well as in the pharmaceutical industry. To meet this demand, optimization of nutritional as …

Microbial Asparaginase and Its Bioprocessing Significance

S Calderón‐Toledo, AI Zavaleta… - Microbial Bioreactors …, 2023 - Wiley Online Library
Summary l‐Asparaginase hydrolyzes l‐asparagine to l‐aspartic acid and releases
ammonium in a two‐step process, which is used in the treatment of leukemia. In this regard …

[PDF][PDF] Fungal L-asparaginases-A mini review

AK Meghavarnam, R Sahu, S Janakiraman - 2022 - fungiindia.co.in
L-asparaginase is an enzyme that catalyzes the hydrolysis of L-asparagine to L-aspartic
acid and ammonia. These enzymes are mainly produced by microbes. Microbial L …

Production and Partial Purification of Pectinases Produced by Three Novel Cladosporium Species Isolated from Egypt

AM Moharram, ANA Zohri, AEL Hesham, MAA Maher… - 2022 - researchsquare.com
Based on phenotypic characters and sequencing of the internal transcribed spacers (ITS),
28S Large Subunit (LSU) and partial actin (ACT), three novel species of Cladosporium were …