Cancer cells adopt aerobic glycolysis as the major source of energy and biomass production
for fast cell proliferation. The bifunctional enzyme, 6-phosphofructo-2-kinase/fructose-2, 6 …

Posttranscriptional regulation is a mechanism for the cells to control gene regulation at the
RNA level. In this process, RNA‐binding proteins (RBPs) play central roles and orchestrate …

The epigenetic reprogramming that occurs during the earliest stages of embryonic
development has been described as crucial for the initial events of cell specification and …

The ZFP36 family of RNA-binding proteins acts post-transcriptionally to repress translation
and promote RNA decay. Studies of genes and pathways regulated by the ZFP36 family in …

Glucose transport from the blood into the brain is tightly regulated by brain microvascular
endothelial cells (BMEC), which also use glucose as their primary energy source. To study …

Tristetraprolin (TTP), a well-known RNA-binding protein, primarily affects the expression of
inflammation-related proteins by binding to the targeted AU-rich element in the …

Coronavirus infections induce the expression of multiple proinflammatory cytokines and
chemokines. We have previously shown that in cells infected with gammacoronavirus …

背景与目的: 6-磷酸果糖激酶-2 同工酶3 (6-phosphofructo-2-kinase 3, PFKFB3) 与肿瘤的发生,
发展密切相关, 且对肿瘤细胞的生物学行为具有重要的调节作用. 分析PFKFB3 …

Consumption of excess calories is associated with alterations in lipid and carbohydrate
metabolism in the liver, and often leads to development of metabolic diseases in the liver …

Background and purpose: The 6-phosphofructo-2-kinase 3 (PFKFB3) is closely related to
tumorigenesis and tumor development, and has important regulatory effects on the …