Single-cell microfluidic impedance cytometry: From raw signals to cell phenotypes using data analytics

C Honrado, P Bisegna, NS Swami, F Caselli - Lab on a Chip, 2021 - pubs.rsc.org
The biophysical analysis of single-cells by microfluidic impedance cytometry is emerging as
a label-free and high-throughput means to stratify the heterogeneity of cellular systems …

In vitro methods for measuring the permeability of cell monolayers

R Bednarek - Methods and protocols, 2022 - mdpi.com
Cell monolayers, including endothelial and epithelial cells, play crucial roles in regulating
the transport of biomolecules to underlying tissues and structures via intercellular junctions …

Conformational-switch biosensors as novel tools to support continuous, real-time molecular monitoring in lab-on-a-chip devices

C Parolo, A Idili, J Heikenfeld, KW Plaxco - Lab on a Chip, 2023 - pubs.rsc.org
Recent years have seen continued expansion of the functionality of lab on a chip (LOC)
devices. Indeed LOCs now provide scientists and developers with useful and versatile …

Recent Development of Implantable Chemical Sensors Utilizing Flexible and Biodegradable Materials for Biomedical Applications

C Hu, L Wang, S Liu, X Sheng, L Yin - ACS nano, 2024 - ACS Publications
Implantable chemical sensors built with flexible and biodegradable materials exhibit
immense potential for seamless integration with biological systems by matching the …

Roadmap for electrical impedance spectroscopy for sensing: a tutorial

LA Buscaglia, ON Oliveira, JP Carmo - IEEE Sensors Journal, 2021 - ieeexplore.ieee.org
Electrical impedance spectroscopy has been used extensively for sensing and biosensing
due to the multiple electrical properties that can be interrogated through varying the …

Opportunities in optical and electrical single-cell technologies to study microbial ecosystems

F Mermans, V Mattelin, R Van den Eeckhoudt… - Frontiers in …, 2023 - frontiersin.org
New techniques are revolutionizing single-cell research, allowing us to study microbes at
unprecedented scales and in unparalleled depth. This review highlights the state-of-the-art …

Label-free live cell recognition and tracking for biological discoveries and translational applications

B Chen, Z Yin, BWL Ng, DM Wang, RS Tuan, R Bise… - npj Imaging, 2024 - nature.com
Label-free, live cell recognition (ie instance segmentation) and tracking using computer
vision-aided recognition can be a powerful tool that rapidly generates multi-modal readouts …

Impedance imaging of cells and tissues: Design and applications

R Bounik, F Cardes, H Ulusan, MM Modena… - BME …, 2022 - spj.science.org
Due to their label-free and noninvasive nature, impedance measurements have attracted
increasing interest in biological research. Advances in microfabrication and integrated …

A wearable CMOS impedance to frequency sensing system for non-invasive impedance measurements

A Hedayatipour, S Aslanzadeh… - … Circuits and Systems, 2020 - ieeexplore.ieee.org
In this paper, we demonstrate a novel non-invasive, wearable impedance sensor. The
impedance sensor, using an impedance to frequency measurement, with two modes of …

A semiconductor 96-microplate platform for electrical-imaging based high-throughput phenotypic screening

S Chitale, W Wu, A Mukherjee, H Lannon… - Nature …, 2023 - nature.com
High-content imaging for compound and genetic profiling is popular for drug discovery but
limited to endpoint images of fixed cells. Conversely, electronic-based devices offer label …