[HTML][HTML] XK-associated McLeod syndrome: nonhematological manifestations and relation to VPS13A disease

K Peikert, A Hermann, A Danek - Transfusion Medicine and …, 2022 - karger.com
Background: McLeod syndrome (MLS) is an X-linked multisystemic progressive disorder
caused by loss of function mutations in the XK gene. The rare blood group phenotype of …

Erysense, a lab-on-a-chip-based point-of-care device to evaluate red blood cell flow properties with multiple clinical applications

SM Recktenwald, MGM Lopes, S Peter, S Hof… - Frontiers in …, 2022 - frontiersin.org
In many medical disciplines, red blood cells are discovered to be biomarkers since they
“experience” various conditions in basically all organs of the body. Classical examples are …

Effect of cell age and membrane rigidity on red blood cell shape in capillary flow

M Nouaman, A Darras, T John, G Simionato, MAE Rab… - Cells, 2023 - mdpi.com
Blood flow in the microcirculatory system is crucially affected by intrinsic red blood cell
(RBC) properties, such as their deformability. In the smallest vessels of this network, RBCs …

Red blood cell lingering modulates hematocrit distribution in the microcirculation

Y Rashidi, G Simionato, Q Zhou, T John, A Kihm… - Biophysical …, 2023 - cell.com
The distribution of red blood cells (RBCs) in the microcirculation determines the oxygen
delivery and solute transport to tissues. This process relies on the partitioning of RBCs at …

[HTML][HTML] Physiological and Pathogenesis Significance of Chorein in Health and Disease

S ALKAHTANI, AA ALKAHTANE… - Physiological …, 2024 - ncbi.nlm.nih.gov
This comprehensive review explores the physiological and pathophysiological significance
of VPS13A, a protein encoded by the VPS13A gene. The VPS13A gene is associated with …

[HTML][HTML] Confinement effect on the microcapillary flow and shape of red blood cells

M Nouaman, A Darras, C Wagner, SM Recktenwald - Biomicrofluidics, 2024 - pubs.aip.org
The ability to change shape is essential for the proper functioning of red blood cells (RBCs)
within the microvasculature. The shape of RBCs significantly influences blood flow and has …

Cell-free layer development and spatial organization of healthy and rigid red blood cells in a microfluidic bifurcation

Y Rashidi, O Aouane, A Darras, T John, J Harting… - Soft Matter, 2023 - pubs.rsc.org
Bifurcations and branches in the microcirculation dramatically affect blood flow as they
determine the spatiotemporal organization of red blood cells (RBCs). Such changes in …

Imaging erythrocyte sedimentation in whole blood

A Darras, HG Breunig, T John, R Zhao, J Koch… - Frontiers in …, 2022 - frontiersin.org
The erythrocyte sedimentation rate (ESR) is one of the oldest medical diagnostic tools.
However, currently there is some debate on the structure formed by the cells during the …

Morphology, repulsion, and ordering of red blood cells in viscoelastic flows under confinement

SM Recktenwald, Y Rashidi, I Graham, PE Arratia… - Soft Matter, 2024 - pubs.rsc.org
Red blood cells (RBC), the primary carriers of oxygen in the body, play a crucial role across
several biomedical applications, while also being an essential model system of a …

Commentary: acanthocytes identified in Huntington's disease

K Peikert, A Storch, A Hermann… - Frontiers in …, 2022 - frontiersin.org
Using scanning electron microscopy (SEM), Yu et al. described a significant percentage of
acanthocytes in peripheral blood from a subgroup of patients (four out of 40) diagnosed with …