Microfluidic devices for detection of RNA viruses

A Basiri, A Heidari, MF Nadi… - Reviews in medical …, 2021 - Wiley Online Library
There is a long way to go before the coronavirus disease 2019 (Covid‐19) outbreak comes
under control. qRT‐PCR is currently used for the detection of severe acute respiratory …

Infectious bronchitis virus evolution, diagnosis and control

M Legnardi, CM Tucciarone, G Franzo… - Veterinary Sciences, 2020 - mdpi.com
RNA viruses are characterized by high mutation and recombination rates, which allow a
rapid adaptation to new environments. Most of the emerging diseases and host jumps are …

Rolling circle amplification in integrated microsystems: An uncut gem toward massively multiplexed pathogen diagnostics and genotyping

RRG Soares, N Madaboosi… - Accounts of Chemical …, 2021 - ACS Publications
Conspectus The development of robust methods allowing the precise detection of specific
nucleic acid sequences is of major societal relevance, paving the way for significant …

[HTML][HTML] Pathogen detection on microfluidic platforms: Recent advances, challenges, and prospects

A Jagannath, H Cong, J Hassan, G Gonzalez… - … and Bioelectronics: X, 2022 - Elsevier
Abstract Point-Of-Care (POC) testing has advanced to more affordable and rapid
alternatives by adapting conventional immunoassays and molecular assays (isothermal …

Recent advances in microfluidic paper-based analytical devices toward high-throughput screening

S Boobphahom, M Nguyet Ly, V Soum, N Pyun… - Molecules, 2020 - mdpi.com
Microfluidic paper-based analytical devices (µPADs) have become promising tools offering
various analytical applications for chemical and biological assays at the point-of-care (POC) …

[HTML][HTML] Digital rolling circle amplification–based detection of Ebola and other tropical viruses

S Ciftci, F Neumann, S Abdurahman… - The Journal of Molecular …, 2020 - Elsevier
Emerging tropical viruses have caused serious outbreaks during the recent years, such as
Ebola virus (EBOV) in 2014 and the most recent in 2018 to 2019 in Congo. Thus, immediate …

Nucleic acid-based detection for foodborne virus utilizing microfluidic systems

W Su, D Liang, M Tan - Trends in Food Science & Technology, 2021 - Elsevier
Background Public health events caused by foodborne virus cause huge economic and
social burden to the affected countries. Foodborne virus detection in food is a very arduous …

The sweet detection of rolling circle amplification: Glucose-based electrochemical genosensor for the detection of viral nucleic acid

S Ciftci, R Cánovas, F Neumann, T Paulraj… - Biosensors and …, 2020 - Elsevier
Herein, an isothermal padlock probe-based assay for the simple and portable detection of
pathogens coupled with a glucose oxidase (GOx)-based electrochemical readout is …

Sub-attomole detection of HIV-1 using padlock probes and rolling circle amplification combined with microfluidic affinity chromatography

RRG Soares, JC Varela, U Neogi, S Ciftci… - Biosensors and …, 2020 - Elsevier
Despite significant progress in diagnostics and disease management during the past
decades, human immunodeficiency virus (HIV) infections are still responsible for nearly 1 …

A novel rolling circle amplification-based detection of SARS-CoV-2 with multi-region padlock hybridization

R Kumari, JW Lim, MR Sullivan, R Malampy, C Baush… - Diagnostics, 2022 - mdpi.com
SARS-CoV-2 has remained a global health burden, primarily due to the continuous
evolution of different mutant strains. These mutations present challenges to the detection of …