The future of stem cell therapies of Alzheimer's disease
ZB Wang, ZT Wang, Y Sun, L Tan, JT Yu - Ageing Research Reviews, 2022 - Elsevier
Alzheimer's disease (AD) places a heavy burden on the global economy. There is no
effective disease-modifying treatment available at present. Since the advent of induced …
effective disease-modifying treatment available at present. Since the advent of induced …
[HTML][HTML] Potential use of iPSCs for disease modeling, drug screening, and cell-based therapy for Alzheimer's disease
Alzheimer's disease (AD) is a chronic illness marked by increasing cognitive decline and
nervous system deterioration. At this time, there is no known medication that will stop the …
nervous system deterioration. At this time, there is no known medication that will stop the …
[HTML][HTML] Human stem cell-derived GABAergic interneurons establish efferent synapses onto host neurons in rat epileptic hippocampus and inhibit spontaneous …
E Waloschková, A Gonzalez-Ramos… - International journal of …, 2021 - mdpi.com
Epilepsy is a complex disorder affecting the central nervous system and is characterised by
spontaneously recurring seizures (SRSs). Epileptic patients undergo symptomatic …
spontaneously recurring seizures (SRSs). Epileptic patients undergo symptomatic …
[HTML][HTML] Hippocampal transplants of fetal GABAergic progenitors regulate adult neurogenesis in mice with temporal lobe epilepsy
MN Arshad, S Oppenheimer, J Jeong… - Neurobiology of …, 2022 - Elsevier
GABAergic interneurons play a role in regulating adult neurogenesis within the dentate
gyrus (DG) of the hippocampus. Neurogenesis occurs within a stem cell niche in the …
gyrus (DG) of the hippocampus. Neurogenesis occurs within a stem cell niche in the …
Interneuron Transplantation for Drug-Resistant Epilepsy
DG Southwell - Neurosurgery Clinics, 2024 - neurosurgery.theclinics.com
Medications are the mainstays of epilepsy treatment, yet they fail to control seizures in 30%
to 40% of patients. 1 Epilepsy surgeries, including brain resection, laser ablation, and …
to 40% of patients. 1 Epilepsy surgeries, including brain resection, laser ablation, and …
Development and preclinical assessment of novel therapies for Epilepsy. Exploring the potential of human-derived cell lines and glial cell line-derived neurotrophic …
E Waloschkova - 2022 - portal.research.lu.se
Epilepsy is one of the leading neurological disorders affecting not only patients who suffer
from seizures but also people around them and society in general. The striking one third of …
from seizures but also people around them and society in general. The striking one third of …