Ruminococcus gnavus was first identified in 1974 as a strict anaerobe in the gut of healthy
individuals, and for several decades, its study has been limited to specific enzymes or …

Mucosal surfaces in the gastrointestinal tract are continually exposed to native, commensal
antigens and susceptible to foreign, infectious antigens. Immunoglobulin A (IgA) provides …

Abstract Background and Aims: Recent studies suggest that mitochondrial dysfunction
promotes progression to NASH by aggravating the gut-liver status. However, the underlying …

Recent evidence demonstrates potential links between mitochondrial dysfunction and
inflammatory bowel diseases (IBD). In addition, bidirectional interactions between the …

Mitochondria are key cellular organelles whose main function is maintaining cell
bioenergetics by producing ATP through oxidative phosphorylation. However, mitochondria …

Dysbiosis is a prominent factor in numerous inflammatory conditions, with Ruminococcus
gnavus, a prevalent gut microbe, implicated in inflammatory bowel disease (IBD), irritable …

Gastroduodenal inflammation and ulcerative injuries are increasing due to expanding socio-
economic stress, unhealthy food habits-lifestyle, smoking, alcoholism and usage of …

Introduction. Inflammatory bowel disease (IBD), which includes Crohn's disease (CD) and
ulcerative colitis (UC), is a multifactorial intestinal disorder but its precise etiology remains …

Inflammatory bowel disease (IBD) is one of the leading gut chronic inflammation disorders,
especially prevalent in Western countries. Recent research suggests that mitochondria play …

Anti-TNF therapy can induce and maintain a remission status during intestinal bowel
disease. However, up to 30% of patients do not respond to this therapy by mechanisms that …