Inflammation is strictly associated with cancer and plays a key role in tumor development
and progression. Several epidemiological studies have demonstrated that inflammation can …

Cancer is one of the most common causes of death globally. Despite extensive research
and considerable advances in cancer therapy, the fundamentals of the disease remain …

CREB is a transcription factor that regulates diverse cellular responses, including
proliferation, survival, and differentiation. CREB is induced by a variety of growth factors and …

Cancer is a complex disease resulting from abnormal cell growth that is induced by a
number of genetic and environmental factors. The tumor microenvironment (TME), which …

Altered expression and function of the transcription factor cyclic AMP response-binding
protein (CREB) has been identified to play an important role in cancer and is associated with …

Receptor-tyrosine-kinase-like orphan receptor 1 (ROR1) is expressed during
embryogenesis and by certain leukemias, but not by normal adult tissues. Here we show …

ROR1 is an orphan-receptor tyrosine-kinase-like surface antigen that is expressed by many
tissues during embryogenesis, some B-cell malignancies, and various cancer cell lines but …

Transcription factors are key regulators of the pattern of gene expression in a cell and
directly control central processes such as proliferation, survival, self-renewal, and invasion …

MicroRNAs are subject to precise regulation and have key roles in tumorigenesis. In contrast
to the oncogenic role of miR-22 reported in myelodysplastic syndrome (MDS) and breast …

Diffuse infiltration is the main reason for therapeutic resistance and recurrence in
glioblastoma (GBM). However, potential targeted therapies for GBM stem-like cell (GSC) …